Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy
Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …
Structure of SARS-CoV-2 spike protein
The COVID-19 (coronavirus disease 2019) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has led to loss of human life in millions and …
syndrome coronavirus 2 (SARS-CoV-2), has led to loss of human life in millions and …
SARS-CoV-2 501Y. V2 escapes neutralization by South African COVID-19 donor plasma
Abstract SARS-CoV-2 501Y. V2 (B. 1.351), a novel lineage of coronavirus causing COVID-
19, contains substitutions in two immunodominant domains of the spike protein. Here, we …
19, contains substitutions in two immunodominant domains of the spike protein. Here, we …
Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
KR McCarthy, LJ Rennick, S Nambulli… - Science, 2021 - science.org
Zoonotic pandemics, such as that caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), can follow the spillover of animal viruses into highly susceptible human …
2 (SARS-CoV-2), can follow the spillover of animal viruses into highly susceptible human …
Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
INTRODUCTION Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
Neutralizing antibodies (nAbs) elicited against the receptor binding site (RBS) of the spike
protein of wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …
protein of wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are …
[HTML][HTML] SARS-CoV-2 variant B. 1.1. 7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines
All current vaccines for COVID-19 utilize ancestral SARS-CoV-2 spike with the goal of
generating protective neutralizing antibodies. The recent emergence and rapid spread of …
generating protective neutralizing antibodies. The recent emergence and rapid spread of …
[HTML][HTML] Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses
KO Saunders, E Lee, R Parks, DR Martinez, D Li… - Nature, 2021 - nature.com
Betacoronaviruses caused the outbreaks of severe acute respiratory syndrome (SARS) and
Middle East respiratory syndrome, as well as the current pandemic of SARS coronavirus 2 …
Middle East respiratory syndrome, as well as the current pandemic of SARS coronavirus 2 …
Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy
Monoclonal antibodies with neutralizing activity against SARS-CoV-2 have demonstrated
clinical benefits in cases of mild-to-moderate SARS-CoV-2 infection, substantially reducing …
clinical benefits in cases of mild-to-moderate SARS-CoV-2 infection, substantially reducing …
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
DR Martinez, A Schäfer, SR Leist, G De la Cruz, A West… - Science, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV) in 2003 and
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies against …
SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies against …