Antibiotics for exacerbations of chronic obstructive pulmonary disease

DJ Vollenweider, A Frei… - Cochrane Database …, 2018 - cochranelibrary.com
Background Many patients with an exacerbation of chronic obstructive pulmonary disease
(COPD) are treated with antibiotics. However, the value of antibiotics remains uncertain, as …

Short-course antibiotic treatment in acute exacerbations of chronic bronchitis and COPD: a meta-analysis of double-blind studies

R El Moussaoui, BM Roede, P Speelman, P Bresser… - Thorax, 2008 - thorax.bmj.com
Background: A study was undertaken to determine whether a short course of antibiotic
treatment (⩽ 5 days) is as effective as the conventional longer treatment in acute …

Moxifloxacin versus amoxicillin/clavulanic acid in outpatient acute exacerbations of COPD: MAESTRAL results

R Wilson, A Anzueto, M Miravitlles… - European …, 2012 - Eur Respiratory Soc
Bacterial infections causing acute exacerbations of chronic obstructive pulmonary disease
(AECOPD) frequently require antibacterial treatment. More evidence is needed to guide …

Assessing treatment success or failure as an outcome in randomised clinical trials of COPD exacerbations. A meta-epidemiological study

AG Mathioudakis, S Ananth, T Bradbury, B Csoma… - Biomedicines, 2021 - mdpi.com
A recently published ERS core outcome set recommends that all trials of COPD
exacerbation management should assess the treatment success (or “cure” of the …

Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for Its High Antimicrobial Activity

M Yamada, T Watanabe, T Miyara, N Baba… - Antimicrobial agents …, 2007 - Am Soc Microbiol
Cefditoren is the active form of cefditoren pivoxil, an oral cephalosporin antibiotic used for
the treatment of respiratory tract infections and otitis media caused by bacteria such as …

Revisiting cefditoren for the treatment of community-acquired infections caused by human-adapted respiratory pathogens in adults

MJ Giménez, L Aguilar, JJ Granizo - Multidisciplinary Respiratory …, 2018 - Springer
Fifteen years after its licensure, this revision assesses the role of cefditoren facing the
current pharmacoepidemiology of resistances in respiratory human-adapted pathogens …

The management of acute bronchitis in children

DM Fleming, AJ Elliot - Expert Opinion on Pharmacotherapy, 2007 - Taylor & Francis
Acute bronchitis is one of the most common infections reported in children under 5 years of
age, and is a leading cause of hospitalisation. In general practice, confusion surrounds the …

Cefditoren versus levofloxacin in patients with exacerbations of chronic bronchitis: serum inflammatory biomarkers, clinical efficacy, and microbiological eradication

F Blasi, P Tarsia, M Mantero… - … and clinical risk …, 2013 - Taylor & Francis
Background The aim of this open-label, randomized, parallel-group pilot study was to
evaluate the efficacy of cefditoren pivoxil and levofloxacin in terms of speed of reduction in …

Tratamiento antimicrobiano de la agudización de la EPOC: Documento de Consenso 2007

M Miravitlles, E Monsó, J Mensa, JA Pérez… - … -Medicina de Familia, 2008 - Elsevier
La gravedad de la agudización de la EPOC viene dada por el grado de la alteración
funcional del paciente en fase estable, por lo que las mediciones espirométricas constituyen …

Antibiotic susceptibility of respiratory pathogens recently isolated in Italy: focus on cefditoren

G Tempera, PM Furneri, NA Carlone… - Journal of …, 2010 - Taylor & Francis
The aim of this study was to evaluate the in vitro antibiotic susceptibility of respiratory
pathogens recently isolated in italy to commonly used antibiotics including cefditoren. Six …