[HTML][HTML] PD-1/PD-L1 pathway: current researches in cancer

Y Han, D Liu, L Li - American journal of cancer research, 2020 - ncbi.nlm.nih.gov
Cancer immunotherapy has been accompanied by promising results over the past few
years. Programmed Cell Death Protein 1 (PD-1) plays a vital role in inhibiting immune …

[HTML][HTML] miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges

S Zhou, J Jin, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …

miRNAs as cornerstones in adipogenesis and obesity

SY Elkhawaga, A Ismail, EGE Elsakka, AS Doghish… - Life Sciences, 2023 - Elsevier
In recent decades, obesity has extensively emerged to the level of pandemics. It's
significantly associated with serious co-morbidities that could decrease life quality and even …

The clinical potential of circulating microRNAs in obesity

C Ji, X Guo - Nature Reviews Endocrinology, 2019 - nature.com
Obesity is a complex condition that is characterized by excessive fat accumulation, which
can lead to the development of metabolic disorders, such as type 2 diabetes mellitus …

miR‐155: an important role in inflammation response

J Hu, S Huang, X Liu, Y Zhang… - Journal of immunology …, 2022 - Wiley Online Library
MicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to
posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in …

miR-155 in cancer drug resistance and as target for miRNA-based therapeutics

R Bayraktar, K Van Roosbroeck - Cancer and Metastasis Reviews, 2018 - Springer
Small non-coding microRNAs (miRNAs) are instrumental in physiological processes, such
as proliferation, cell cycle, apoptosis, and differentiation, processes which are often …

siRNA-and miRNA-based therapeutics for liver fibrosis

Z Zhao, CY Lin, K Cheng - Translational Research, 2019 - Elsevier
Liver fibrosis is a wound-healing process induced by chronic liver injuries, such as
nonalcoholic steatohepatitis, hepatitis, alcohol abuse, and metal poisoning. The …

Deciphering signaling pathway interplay via miRNAs in malignant pleural mesothelioma

A Salman, SSA Mageed, D Fathi, MA Elrebehy… - … -Research and Practice, 2023 - Elsevier
Malignant pleural mesothelioma (MPM) is a highly invasive form of lung cancer that
adversely affects the pleural and other linings of the lungs. MPM is a very aggressive tumor …

[HTML][HTML] The dual role of microRNAs in colorectal cancer progression

L Ding, Z Lan, X Xiong, H Ao, Y Feng, H Gu… - International journal of …, 2018 - mdpi.com
Colorectal cancer (CRC) is responsible for one of the major cancer incidence and mortality
worldwide. It is well known that MicroRNAs (miRNAs) play vital roles in maintaining the cell …

Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy

Y Li, Y Duo, J Bi, X Zeng, L Mei, S Bao… - International journal …, 2018 - Taylor & Francis
Introduction MicroRNA-155 (miR-155) is an oncogenic microRNA, which is upregulated in
many human cancers including colorectal cancer (CRC). Overexpression of miR-155 has …