[PDF][PDF] Search for new targets of deep brain stimulation for epilepsy treatment

L Huang, E van Luijtelaar - 2016 - repository.ubn.ru.nl
Although clinical trials in refractory epilepsy are currently carried out, the field of deep brain
stimulation (DBS) in epilepsy is still at its initial stage. Little is known about where, when and …

Applications of long-term data from neurostimulation devices

P Dugan, VR Rao - Neurostimulation for Epilepsy, 2023 - Elsevier
Three neurostimulation therapies have been approved for use in drug-resistant focal
epilepsies: vagus nerve stimulation (VNS), deep brain stimulation (DBS), and responsive …

[HTML][HTML] High-frequency and brief-pulse stimulation pulses terminate cortical electrical stimulation-induced afterdischarges

Z Ren, Y Li, T Yu, D Ni, G Zhang, W Du… - Neural Regeneration …, 2017 - journals.lww.com
Brief-pulse stimulation at 50 Hz has been shown to terminate afterdischarges observed in
epilepsy patients. However, the optimal pulse stimulation parameters for terminating cortical …

Subicular pyramidal neurons: A key to unlock the “black box” of drug resistance in temporal lobe epilepsy

Z Hu, X Wang, K Zhong - Neuroscience Bulletin, 2019 - Springer
Drug resistance is one of the most serious issues in epilepsy. Despite using various
appropriate anti-epileptic drugs (AEDs), 30% of epilepsy patients are still drugresistant. The …

Short-term amygdala low-frequency stimulation does not influence hippocampal interneuron changes observed in the pilocarpine model of epilepsy. Cells 2021; 10

I Mihály, T Molnár, ÁJ Berki, RB Bod, K Orbán-Kis… - 2021 - search.proquest.com
Temporal lobe epilepsy (TLE) is characterized by changes in interneuron numbers in the
hippocampus. Deep brain stimulation (DBS) is an emerging tool to treat TLE seizures …

高频短脉冲刺激更能有效抑制皮质电刺激引起的后放电

Z Ren, Y Li, T Yu, D Ni, G Zhang, W Du… - 中国神经再生研究 …, 2017 - sjzsyj.com.cn
既往研究中多采用50Hz 的短脉冲刺激终止癫痫患者的后放电, 但这是否为抑制皮质电刺激引起
后放电的最佳刺激参数, 目前尚无结论. 试验为观察不同频率刺激对人大脑皮质电刺激引起后 …

[HTML][HTML] 藏红花素对小鼠电点燃癫痫的影响

W Xiting, T Oufeng, YE Yilu, M ZHENG… - Journal of Zhejiang …, 2017 - ncbi.nlm.nih.gov
藏红花素对小鼠电点燃癫痫的影响- PMC Back to Top Skip to main content NIH NLM Logo Access
keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Preview …

Combined multi-frequency responsive stimulation for effective seizure suppression in temporal lobe epilepsy model

F Zhang, Y Zheng, C Yu, HC Wu… - 2019 IEEE Biomedical …, 2019 - ieeexplore.ieee.org
Single-target responsive neural stimulation might underlie limited efficacy for seizure
suppression since broad networks in the brain are involved in the epileptic activities. In order …

Predicting Pharmacoresistance in Drug-Naïve Temporal Lobe Epilepsy Using Ictal EEGs

Z Chen, Y Gong, C Xu, Z Zhang, S Zhang, X Li, X Qiu… - papers.ssrn.com
Background: One-third of patients with epilepsy are resistant to pharmacological
interventions. Early prediction of pharmacoresistance is therapeutically significant to …

Control of epileptic seizures by electrical low frequency deep brain stimulation: a review of probable mechanisms.

M Zare, A Shojaei, SJ Mirnajarizadeh - 2020 - cabidigitallibrary.org
Epilepsy is the most common neurological disease with no definitive method in treatment.
Notably, the main way to treat and control epileptic seizures is drug therapy. However, about …