Characterization of CYP2C19 pharmacogenetic variation in African populations and comparison with other global populations

RP Booyse, D Twesigomwe, S Hazelhurst - Pharmacogenomics, 2023 - Future Medicine
Background: CYP2C19 is important in the metabolism of clopidogrel and several
antidepressants. This study aimed to characterize the distribution of CYP2C19 star alleles …

[PDF][PDF] Characterisation of variation in the CYP2C19 gene in African populations

RP Booyse - 2023 - wiredspace.wits.ac.za
Abstract Cytochrome P450 2C19 (CYP2C19) is highly polymorphic, and this accounts in part
for variability in response to clopidogrel and anti-depressants worldwide. However …