Life of RISC: Formation, action, and degradation of RNA-induced silencing complex
Small RNAs regulate a wide variety of biological processes by repressing the expression of
target genes at the transcriptional and post-transcriptional levels. To achieve these …
target genes at the transcriptional and post-transcriptional levels. To achieve these …
[HTML][HTML] CLIP and complementary methods
RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …
miRDB: an online database for prediction of functional microRNA targets
MicroRNAs (miRNAs) are small noncoding RNAs that act as master regulators in many
biological processes. miRNAs function mainly by downregulating the expression of their …
biological processes. miRNAs function mainly by downregulating the expression of their …
Regulation of microRNA function in animals
LFR Gebert, IJ MacRae - Nature reviews Molecular cell biology, 2019 - nature.com
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …
key regulators of biological processes in animals. These small RNAs form complex networks …
The biochemical basis of microRNA targeting efficacy
INTRODUCTION MicroRNAs (miRNAs) are short RNAs that guide repression of mRNA
targets. Each miRNA associates with an Argonaute (AGO) protein to form a complex in …
targets. Each miRNA associates with an Argonaute (AGO) protein to form a complex in …
Prediction of functional microRNA targets by integrative modeling of microRNA binding and target expression data
We perform a large-scale RNA sequencing study to experimentally identify genes that are
downregulated by 25 miRNAs. This RNA-seq dataset is combined with public miRNA target …
downregulated by 25 miRNAs. This RNA-seq dataset is combined with public miRNA target …
[HTML][HTML] Metazoan micrornas
DP Bartel - Cell, 2018 - cell.com
MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …
DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA–gene interactions
D Karagkouni, MD Paraskevopoulou… - Nucleic acids …, 2018 - academic.oup.com
Abstract DIANA-TarBase v8 (http://www. microrna. gr/tarbase) is a reference database
devoted to the indexing of experimentally supported microRNA (miRNA) targets. Its eighth …
devoted to the indexing of experimentally supported microRNA (miRNA) targets. Its eighth …
Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function
INTRODUCTION Recently, a special class of RNAs has excited researchers and triggered
hundreds of now-published studies. Known as circular RNAs (circRNAs), these RNAs are …
hundreds of now-published studies. Known as circular RNAs (circRNAs), these RNAs are …
DIANA-LncBase v3: indexing experimentally supported miRNA targets on non-coding transcripts
D Karagkouni, MD Paraskevopoulou… - Nucleic acids …, 2020 - academic.oup.com
Abstract DIANA-LncBase v3. 0 (www. microrna. gr/LncBase) is a reference repository with
experimentally supported miRNA targets on non-coding transcripts. Its third version provides …
experimentally supported miRNA targets on non-coding transcripts. Its third version provides …