ADHD co-morbidities: A review of implication of gene× environment effects with dopamine-related genes

M Kanarik, O Grimm, NR Mota, A Reif… - … & Biobehavioral Reviews, 2022 - Elsevier
ADHD is a major burden in adulthood, where co-morbid conditions such as depression,
substance use disorder and obesity often dominate the clinical picture. ADHD has …

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis, R Walters… - Nature …, 2023 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
with a major genetic component. Here, we present a genome-wide association study meta …

Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes

M Ribasés, M Mitjans, CA Hartman, MS Artigas… - Neuroscience & …, 2023 - Elsevier
Attention-deficit/hyperactivity disorder (ADHD) co-occurs with many other psychiatric
disorders and traits. In this review, we summarize and interpret the existing literature on the …

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

D Demontis, GB Walters, G Athanasiadis, R Walters… - MedRxiv, 2022 - medrxiv.org
Attention deficit hyperactivity disorder (ADHD) is a prevalent childhood psychiatric disorder,
with a major genetic component. Here we present a GWAS meta-analysis of ADHD …

Working memory and reaction time variability mediate the relationship between polygenic risk and ADHD traits in a general population sample

M Moses, J Tiego, D Demontis, G Bragi Walters… - Molecular …, 2022 - nature.com
Endophenotypes are heritable and quantifiable traits indexing genetic liability for a disorder.
Here, we examined three potential endophenotypes, working memory function, response …

Longer screen time utilization is associated with the polygenic risk for attention-deficit/hyperactivity disorder with mediation by brain white matter microstructure

A Yang, ET Rolls, G Dong, J Du, Y Li, J Feng… - …, 2022 - thelancet.com
Background Attention-deficit/hyperactivity disorder (ADHD) has been reported to be
associated with longer screen time utilization (STU) at the behavioral level. However …

Three decades of ASD genetics: building a foundation for neurobiological understanding and treatment

KW Eyring, DH Geschwind - Human Molecular Genetics, 2021 - academic.oup.com
Methodological advances over the last three decades have led to a profound transformation
in our understanding of the genetic origins of neuropsychiatric disorders. This is exemplified …

Autism spectrum disorder and attention-deficit/hyperactivity disorder: shared or unique neurocognitive profiles?

RJ Schachar, A Dupuis, PD Arnold… - Research on Child and …, 2023 - Springer
Abstract Attention-deficit/hyperactivity (ADHD) and autism spectrum (ASD) disorders are
commonly co-occurring conditions characterized by neurocognitive impairments. Few …

Autistic traits are associated with faster pace of aging: Evidence from the Dunedin study at age 45

D Mason, A Ronald, A Ambler, A Caspi… - Autism …, 2021 - Wiley Online Library
Growing evidence indicates that the defining characteristics of autism spectrum disorder
(ASD) are distributed throughout the general population; hence, understanding the …

[HTML][HTML] New research perspectives on the interplay between genes and environment on executive function development

PM Miguel, MJ Meaney, PP Silveira - Biological Psychiatry, 2023 - Elsevier
Executive functions (EFs) are a set of skills responsible for the cognitive control of emotional
states and behavior as well as for information processing required for learning and memory …