Oxidative stress (OS), caused by the imbalance between the generation and detoxification of
reactive oxygen and nitrogen species (ROS/RNS), plays an important role in brain aging …

Abstract Arsenic (As) and selenium (Se) are unusual metalloids as they both induce and
cure cancer. They both cause carcinogenesis, pathology, cytotoxicity, and genotoxicity in …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Stroke is one of the leading causes of mortality and morbidity, with astronomical financial
repercussions on health systems worldwide. Ischaemic stroke accounts for approximately 80 …

Oxidative stress is a phenomenon associated with pathogenetic mechanisms of several
diseases including atherosclerosis, neurodegenerative diseases, such as Alzheimer's and …

Redox state is a term used widely in the research field of free radicals and oxidative stress.
Unfortunately, it is used as a general term referring to relative changes that are not well …

In this review, primary attention is given to the antioxidant (and prooxidant) activity of
polyphenols arising from their interactions with iron both in vitro and in vivo. In addition, an …

Oxidative stress has been implicated in the progression of Alzheimer's disease, Parkinson's
disease and amyotrophic lateral sclerosis. Oxygen is vital for life but is also potentially …

Abstract Beckman, Kenneth B., and Bruce N. Ames. The Free Radical Theory of Aging
Matures. Physiol. Rev. 78: 547–581, 1998.—The free radical theory of aging, conceived in …

Reactive oxygen species (ROS) are generated as by-products of cellular metabolism,
primarily in the mitochondria. When cellular production of ROS overwhelms its antioxidant …