The lactoferrin phenomenon—a miracle molecule

P Kowalczyk, K Kaczyńska, P Kleczkowska… - Molecules, 2022 - mdpi.com
Numerous harmful factors that affect the human body from birth to old age cause many
disturbances, eg, in the structure of the genome, inducing cell apoptosis and their …

[HTML][HTML] Iron in infection and immunity

M Nairz, G Weiss - Molecular Aspects of Medicine, 2020 - Elsevier
Iron is an essential micronutrient for virtually all living cells. In infectious diseases, both
invading pathogens and mammalian cells including those of the immune system require iron …

The biology of lactoferrin, an iron-binding protein that can help defend against viruses and bacteria

DB Kell, EL Heyden, E Pretorius - Frontiers in immunology, 2020 - frontiersin.org
Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …

Immune-boosting, antioxidant and anti-inflammatory food supplements targeting pathogenesis of COVID-19

M Mrityunjaya, V Pavithra, R Neelam… - Frontiers in …, 2020 - frontiersin.org
The COVID-19 is an acute and contagious disease characterized by pneumonia and ARDS.
The disease is caused by SARS-CoV-2, which belongs to the family of Coronaviridae along …

Iron metabolism in obesity and metabolic syndrome

Á González-Domínguez, FM Visiedo-García… - International journal of …, 2020 - mdpi.com
Obesity is an excessive adipose tissue accumulation that may have detrimental effects on
health. Particularly, childhood obesity has become one of the main public health problems in …

[HTML][HTML] Invited review: Acid whey trends and health benefits

D Rocha-Mendoza, E Kosmerl, A Krentz, L Zhang… - Journal of Dairy …, 2021 - Elsevier
In recent years, acid whey production has increased due to a growing demand for Greek
yogurt and acid-coagulated cheeses. Acid whey is a dairy by-product for which the industry …

Lactoferrin as potential preventative and adjunct treatment for COVID-19

R Chang, TB Ng, WZ Sun - International Journal of Antimicrobial Agents, 2020 - Elsevier
ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic is rapidly advancing
across the globe despite drastic public and personal health measures. Antivirals and …

Diverse mechanisms of antimicrobial activities of lactoferrins, lactoferricins, and other lactoferrin-derived peptides

Š Gruden, N Poklar Ulrih - International journal of molecular sciences, 2021 - mdpi.com
Lactoferrins are an iron-binding glycoprotein that have important protective roles in the
mammalian body through their numerous functions, which include antimicrobial, antitumor …

Lactoferrin's anti-cancer properties: Safety, selectivity, and wide range of action

A Cutone, L Rosa, G Ianiro, MS Lepanto… - Biomolecules, 2020 - mdpi.com
Despite recent advances in cancer therapy, current treatments, including radiotherapy,
chemotherapy, and immunotherapy, although beneficial, present attendant side effects and …

Iron and chelation in biochemistry and medicine: new approaches to controlling iron metabolism and treating related diseases

GJ Kontoghiorghes, CN Kontoghiorghe - Cells, 2020 - mdpi.com
Iron is essential for all living organisms. Many iron-containing proteins and metabolic
pathways play a key role in almost all cellular and physiological functions. The diversity of …