Zinc oxide nanoparticles: Synthesis, antiseptic activity and toxicity mechanism

A Król, P Pomastowski, K Rafińska… - Advances in colloid and …, 2017 - Elsevier
Zinc oxide (ZnO), as a material with attractive properties, has attracted great interest
worldwide, particularly owing to the implementation of the synthesis of nano-sized particles …

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

JS Suk, Q Xu, N Kim, J Hanes, LM Ensign - Advanced drug delivery reviews, 2016 - Elsevier
Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …

Hydrogels in controlled release formulations: network design and mathematical modeling

CC Lin, AT Metters - Advanced drug delivery reviews, 2006 - Elsevier
Over the past few decades, advances in hydrogel technologies have spurred development
in many biomedical applications including controlled drug delivery. Many novel hydrogel …

Intranasal vaccine: Factors to consider in research and development

H Xu, L Cai, S Hufnagel, Z Cui - International journal of pharmaceutics, 2021 - Elsevier
Most existing vaccines for human use are administered by needle-based injection.
Administering vaccines needle-free intranasally has numerous advantages over by needle …

Nanoparticles for direct nose-to-brain delivery of drugs

A Mistry, S Stolnik, L Illum - International journal of pharmaceutics, 2009 - Elsevier
This review aims to evaluate the evidence for the existence of a direct nose-to-brain delivery
route for nanoparticles administered to the nasal cavity and transported via the olfactory …

In Vitro Cytotoxicity of Nanoparticles in Mammalian Germline Stem Cells

L Braydich-Stolle, S Hussain, JJ Schlager… - Toxicological …, 2005 - academic.oup.com
Gametogenesis is a complex biological process that is particularly sensitive to
environmental insults such as chemicals. Many chemicals have a negative impact on the …

Intranasal delivery: physicochemical and therapeutic aspects

HR Costantino, L Illum, G Brandt, PH Johnson… - International journal of …, 2007 - Elsevier
Interest in intranasal (IN) administration as a non-invasive route for drug delivery continues
to grow rapidly. The nasal mucosa offers numerous benefits as a target issue for drug …

In Vitro and in Vivo mRNA Delivery Using Lipid-Enveloped pH-Responsive Polymer Nanoparticles

X Su, J Fricke, DG Kavanagh… - Molecular pharmaceutics, 2011 - ACS Publications
Biodegradable core− shell structured nanoparticles with a poly (β-amino ester)(PBAE) core
enveloped by a phospholipid bilayer shell were developed for in vivo mRNA delivery with a …

Toxicology of nanomaterials used in nanomedicine

J Zhao, V Castranova - Journal of Toxicology and Environmental …, 2011 - Taylor & Francis
With the development of nanotechnology, nanomaterials are being widely used in many
industries as well as in medicine and pharmacology. Despite the many proposed …

Toxicity evaluation of biodegradable chitosan nanoparticles using a zebrafish embryo model

YL Hu, W Qi, F Han, JZ Shao… - International journal of …, 2011 - Taylor & Francis
Background Although there are a number of reports regarding the toxicity evaluation of
inorganic nanoparticles, knowledge on biodegradable nanomaterials, which have always …