[HTML][HTML] Potential herb–drug interactions between anti-COVID-19 drugs and traditional Chinese medicine
L Ye, S Fan, P Zhao, C Wu, M Liu, S Hu, P Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …
COVID-19 therapeutics
Since the emergence of COVID-19 in 2020, an unprecedented range of therapeutic options
has been studied and deployed. Healthcare providers have multiple treatment approaches …
has been studied and deployed. Healthcare providers have multiple treatment approaches …
New design of an activity assay suitable for high-throughput screening of substrates and inhibitors of the mitochondrial amidoxime reducing component (mARC)
The mitochondrial amidoxime-reducing component (mARC) is one of the simplest
molybdenum-containing enzymes. mARC is among a few known reducing enzymes playing …
molybdenum-containing enzymes. mARC is among a few known reducing enzymes playing …
[HTML][HTML] Molnupiravir Revisited—Critical Assessment of Studies in Animal Models of COVID-19
HB Rasmussen, PR Hansen - Viruses, 2023 - mdpi.com
Molnupiravir, a prodrug known for its broad antiviral activity, has demonstrated efficacy in
animal models of COVID-19, prompting clinical trials, in which initial results indicated a …
animal models of COVID-19, prompting clinical trials, in which initial results indicated a …
[HTML][HTML] Insights into COVID-19: Perspectives on Drug Remedies and Host Cell Responses
AM Awad, K Hansen, D Del Rio, D Flores… - Biomolecules, 2023 - mdpi.com
In light of the COVID-19 global pandemic caused by SARS-CoV-2, ongoing research has
centered on minimizing viral spread either by stopping viral entry or inhibiting viral …
centered on minimizing viral spread either by stopping viral entry or inhibiting viral …
[HTML][HTML] Further preclinical characterization of molnupiravir against SARS-CoV-2: Antiviral activity determinants and viral genome alteration patterns
The SARS-CoV-2 pandemic has highlighted the need for broad-spectrum antiviral drugs to
respond promptly to viral emergence. We conducted a preclinical study of molnupiravir …
respond promptly to viral emergence. We conducted a preclinical study of molnupiravir …
In vitro and in vivo validation of the antiviral effect of hCypA against SARS-CoV-2 via binding to the RBD of spike protein
The novel coronavirus disease 2019 has stimulated the rapid development of new biological
therapeutics to inhibit SARS-CoV-2 infection; however, this remains a challenging task. In a …
therapeutics to inhibit SARS-CoV-2 infection; however, this remains a challenging task. In a …
Development and Validation of In-vitro Release Study of Molnupiravir Capsules by RP-HPLC
Introduction: The coronavirus disease-2019 (COVID-19) outbreak all over the world has led
researchers to strive to develop treatment and preventive measures to control its …
researchers to strive to develop treatment and preventive measures to control its …
In Vitro and in Vivo Evaluation Tools of SARS-CoV-2 Antiviral Drugs
GK Sharma, S Nehul, S Choudhary… - Advances in Antiviral …, 2024 - Springer
We have outlined the in vitro and preclinical methods for the assessment of the therapeutic
properties of compounds against SARS-CoV2 in this chapter. Various criteria, which should …
properties of compounds against SARS-CoV2 in this chapter. Various criteria, which should …
Immunobiology of COVID-19: Mechanistic and therapeutic insights from animal models
HY Zheng, TZ Song, YT Zheng - Zoological research, 2024 - pubmed.ncbi.nlm.nih.gov
The distribution of the immune system throughout the body complicates in vitro assessments
of coronavirus disease 2019 (COVID-19) immunobiology, often resulting in a lack of …
of coronavirus disease 2019 (COVID-19) immunobiology, often resulting in a lack of …