ABCB1, ABCG2, ABCC1, ABCC2, and ABCC3 drug transporter polymorphisms and their impact on drug bioavailability: what is our current understanding?
H Bruckmueller, I Cascorbi - Expert opinion on drug metabolism & …, 2021 - Taylor & Francis
Introduction Interindividual differences in drug response are a frequent clinical challenge
partly due to variation in pharmacokinetics. ATP-binding cassette (ABC) transporters are …
partly due to variation in pharmacokinetics. ATP-binding cassette (ABC) transporters are …
MicroRNAs in cancer therapy: Their involvement in oxaliplatin sensitivity/resistance of cancer cells with a focus on colorectal cancer
The resistance of cancer cells into chemotherapy has restricted the efficiency of anti-tumor
drugs. Oxaliplatin (OX) being an anti-tumor agent/drug is extensively used in the treatment of …
drugs. Oxaliplatin (OX) being an anti-tumor agent/drug is extensively used in the treatment of …
Enzyme-catalyzed synthesis of selenium-doped manganese phosphate for synergistic therapy of drug-resistant colorectal cancer
M Pei, K Liu, X Qu, K Wang, Q Chen, Y Zhang… - Journal of …, 2023 - Springer
Background The development of multidrug resistance (MDR) during postoperative
chemotherapy for colorectal cancer substantially reduces therapeutic efficacy …
chemotherapy for colorectal cancer substantially reduces therapeutic efficacy …
VEGF-634G > C (rs2010963) Gene Polymorphism and High Risk of Breast Cancer in the Northwest of Iran
MS Maghsoodi, NS Khosroshahi… - Indian Journal of …, 2023 - Springer
Introduction Breast cancer (BC) is one of the common diseases with higher cancer death in
women. Vascular endothelial growth factor (VEGF) plays an important role in proliferation …
women. Vascular endothelial growth factor (VEGF) plays an important role in proliferation …
Vascular endothelial growth factor A (VEGFA) promoter rs2010963 polymorphism and cancer risk: An updated meta-analysis and trial sequential analysis
Objectives Previous observational studies evaluating the relationship of VEGFA rs2010963
polymorphism with cancer risk reported inconsistent outcomes. We conducted this meta …
polymorphism with cancer risk reported inconsistent outcomes. We conducted this meta …
The relation of VEGFA, VEGFR2, VEGI, and HIF1A genetic variants and their serum protein levels with breast cancer in Egyptian patients
AA Abdelgalil, R Monir, M Elmetwally, MH Ghattas… - Biochemical …, 2024 - Springer
Breast cancer is the most common type of cancer in Egyptian females. Polymorphisms in the
angiogenesis pathway have been implicated previously in cancer risk and prognosis. The …
angiogenesis pathway have been implicated previously in cancer risk and prognosis. The …
Association of VEGF polymorphisms and breast cancer susceptibility: systemic review and meta-analysis
YS Kumar, S Varghese, L Kulanthaivel, GK Subbaraj - Meta Gene, 2021 - Elsevier
Aim This meta-analysis aimed to evaluate the association between different VEGF gene
polymorphisms (VEGF 2578 C/A, VEGF 936 C/T, VEGF 634 G/C, VEGF 460 T/C and VEGF …
polymorphisms (VEGF 2578 C/A, VEGF 936 C/T, VEGF 634 G/C, VEGF 460 T/C and VEGF …
Correlation between ABCB1 and OLIG2 polymorphisms and the severity and prognosis of patients with cerebral infarction
CY Liang, CY Huang, ZR Nong, SL Li, MS Lin… - Open Medicine, 2024 - degruyter.com
This study investigated the relationship between ATP-binding cassette sub-family B member
1 (ABCB1) and OLIG2 single nucleotide polymorphism (SNP) and neurological injury …
1 (ABCB1) and OLIG2 single nucleotide polymorphism (SNP) and neurological injury …
Using correlation matrix for the investigation the interaction of genes and traditional risk factor in breast cancer
E Nazari, R ArefNezhad, M Tabadkani, AH Farzin… - Meta Gene, 2021 - Elsevier
Background Despite extensive effort, breast cancer (BC) is still among the most lethal cancer
in women. Here we explored the interaction of traditional markers (including pathological …
in women. Here we explored the interaction of traditional markers (including pathological …
[HTML][HTML] Predictive and prognostic significance of loss of heterozygosity in ABC transporter genes in breast cancer
MM Tsyganov, MK Ibragimova… - Сибирский …, 2022 - cyberleninka.ru
ABC-transporter family genes have been well studied and their involvement in the
development of drug resistance has been assessed. The presence of aberrant conditions in …
development of drug resistance has been assessed. The presence of aberrant conditions in …