KIF2C is a prognostic biomarker associated with immune cell infiltration in breast cancer
S Liu, Z Ye, VW Xue, Q Sun, H Li, D Lu - BMC cancer, 2023 - Springer
Background The kinesin-13 family member 2C (KIF2C) is a versatile protein participating in
many biological processes. KIF2C is frequently up-regulated in multiple types of cancer and …
many biological processes. KIF2C is frequently up-regulated in multiple types of cancer and …
Advances in renal cell carcinoma drug resistance models
Y Xiang, G Zheng, J Zhong, J Sheng, H Qin - Frontiers in Oncology, 2022 - frontiersin.org
Renal cell carcinoma (RCC) is the most common form of kidney cancer. Systemic therapy is
the preferred method to eliminate residual cancer cells after surgery and prolong the survival …
the preferred method to eliminate residual cancer cells after surgery and prolong the survival …
Comprehensive analysis illustrating the role of PANoptosis-related genes in lung cancer based on bioinformatic algorithms and experiments
S Wei, Z Chen, X Ling, W Zhang, L Jiang - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: Recently, PANoptosis has aroused the interest of researchers for its role in
cancers. However, the studies that investigated PANoptosis in lung cancer are still few …
cancers. However, the studies that investigated PANoptosis in lung cancer are still few …
The m6A/m5C/m1A regulator genes signature reveals the prognosis and is related with immune microenvironment for hepatocellular carcinoma
T Liu, L Sun, Z Li, K Yang, J Chen, X Han, L Qi… - BMC …, 2023 - Springer
Background RNA methylation is a crucial in many biological functions, and its aberrant
regulation is associated with cancer progression. N6-Methyladenosine (m6A), 5 …
regulation is associated with cancer progression. N6-Methyladenosine (m6A), 5 …
Knockdown of ADAM8 inhibits the proliferation, migration, invasion, and tumorigenesis of renal clear cell carcinoma cells to enhance the immunotherapy efficacy
H Qu, M Mao, K Wang, Z Mu, B Hu - Translational Research, 2024 - Elsevier
The current study performed bioinformatics and in vitro and in vivo experiments to explore
the effects of ADAM8 on the malignant behaviors and immunotherapeutic efficacy of renal …
the effects of ADAM8 on the malignant behaviors and immunotherapeutic efficacy of renal …
Identification of the novel therapeutic targets and biomarkers associated of prostate cancer with cancer-associated fibroblasts (CAFs)
X Zhai, X Chen, Z Wan, M Ge, Y Ding, J Gu… - Frontiers in …, 2023 - frontiersin.org
Globally, prostate cancer remains a leading cause of mortality and morbidity despite
advances in treatment. Research on prostate cancer has primarily focused on the malignant …
advances in treatment. Research on prostate cancer has primarily focused on the malignant …
An innovative model based on N7-methylguanosine-related lncRNAs for forecasting prognosis and tumor immune landscape in bladder cancer
L Ren, X Yang, J Liu, W Wang, Z Liu, Q Lin… - Cancer Cell …, 2023 - Springer
Background As a novel type of the prevalent post-transcriptional modifications, N7-
methylguanosine (m7G) modification is essential in the tumorigenesis, progression, and …
methylguanosine (m7G) modification is essential in the tumorigenesis, progression, and …
CHKB-AS1 enhances proliferation and resistance to NVP-BEZ235 of renal cancer cells via regulating the phosphorylation of MAP4 and PI3K/AKT/mTOR signaling
X Chen, T Zhang, X Ren, Y Wei, X Zhang… - European Journal of …, 2023 - Springer
Targeted therapy is pivotal in renal carcinoma treatment, and the dual-inhibitor NVP-BEZ235
has emerged as a promising candidate in preliminary studies. Its effectiveness against renal …
has emerged as a promising candidate in preliminary studies. Its effectiveness against renal …
The prognostic value and immunological role of CD44 in pan-cancer study
S Chen, S Zhang, S Chen, F Ma - Scientific Reports, 2023 - nature.com
To investigate the correlation between cluster of differentiation-44 (CD44) expression and
immunotherapy response and identify its possible predictive value in pan-cancer. Datasets …
immunotherapy response and identify its possible predictive value in pan-cancer. Datasets …
Investigation of M2 macrophage-related gene affecting patients prognosis and drug sensitivity in non-small cell lung cancer: Evidence from bioinformatic and …
Z Zeng, J Yu, Z Yang, K Du, Y Chen, L Zhou - Frontiers in Oncology, 2022 - frontiersin.org
Background The progression process of lung cancer can be accelerated by M2
macrophages. However, genes that affect M2 macrophage polarization remain unidentified …
macrophages. However, genes that affect M2 macrophage polarization remain unidentified …