Platelet and extracellular vesicles in COVID-19 infection and its vaccines

H Goubran, J Seghatchian, W Sabry, G Ragab… - … and Apheresis Science, 2022 - Elsevier
Platelets are at the crossroads between thrombosis and inflammation. When activated,
platelets can shed bioactive extracellular vesicles [pEVs] that share the hemostatic potential …

[HTML][HTML] COVID-19 diagnosis using clinical markers and multiple explainable artificial intelligence approaches: a case study from Ecuador

K Chadaga, S Prabhu, V Bhat, N Sampathila… - SLAS technology, 2023 - Elsevier
The COVID-19 pandemic erupted at the beginning of 2020 and proved fatal, causing many
casualties worldwide. Immediate and precise screening of affected patients is critical for …

Early fluvoxamine reduces the risk for clinical deterioration in symptomatic outpatients with Covid-19: a real-world, retrospective, before–after analysis

A Tsiakalos, PD Ziakas, E Polyzou, G Schinas… - Microorganisms, 2023 - mdpi.com
Fluvoxamine, a selective serotonin reuptake inhibitor with anti-inflammatory properties, has
gained attention as a repurposed drug to treat COVID-19. We aimed to explore the potential …

Lymphocyte trajectories are associated with prognosis in critically ill patients: a convenient way to monitor immune status

F Pei, W Song, L Wang, L Liang, B Gu, M Chen… - Frontiers in …, 2022 - frontiersin.org
Background Immunosuppression is a risk factor for poor prognosis of critically ill patients, but
current monitoring of the immune status in clinical practice is still inadequate. Absolute …

Results of phase 2 randomized multi-center study to evaluate the safety and efficacy of infusion of memory T cells as adoptive therapy in severe acute respiratory …

C Ferreras, C Hernández-Blanco, A Martín-Quirós… - Cytotherapy, 2024 - Elsevier
Background aims There are currently no effective anti-viral treatments for coronavirus
disease 2019 (COVID-19)–hospitalized patients with hypoxemia. Lymphopenia is a …

Utility of laboratory and immune biomarkers in predicting disease progression and mortality among patients with moderate to severe COVID-19 disease at a Philippine …

FER Punzalan, JAM Aherrera… - Frontiers in …, 2023 - frontiersin.org
Purpose This study was performed to determine the clinical biomarkers and cytokines that
may be associated with disease progression and in-hospital mortality in a cohort of …

Defining the correlates of lymphopenia and independent predictors of poor clinical outcome in adults hospitalized with COVID-19 in Australia

P Hastak, D Cromer, J Malycha, CR Andersen… - Scientific Reports, 2024 - nature.com
Lymphopenia is a common feature of acute COVID-19 and is associated with increased
disease severity and 30-day mortality. Here we aim to define the demographic and clinical …

Cellular immune profiling of lung and blood compartments in patients with SARS-CoV-2 infection

L Santinelli, A Lazzaro, F Sciarra, L Maddaloni… - Pathogens, 2023 - mdpi.com
Background: SARS-CoV-2 related immunopathology may be the driving cause underlying
severe COVID-19. Through an immunophenotyping analysis on paired bronchoalveolar …

Clinical, Laboratory, and Imaging Findings of Pregnant Women with Possible Vertical Transmission of SARS-CoV-2—Case Series

M Craina, D Iacob, M Dima, S Bernad… - International Journal of …, 2022 - mdpi.com
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic
significantly impacted the general population's health. At times, the infection has unfavorably …

Predictors of noninvasive respiratory support failure in covid-19 patients: a prospective observational study

R Zablockis, G Šlekytė, R Mereškevičienė… - Medicina, 2022 - mdpi.com
Background and Objective: Respiratory assistance tactic that is best for COVID-19-
associated acute hypoxemic respiratory failure (AHRF) individuals has yet to be determined …