[HTML][HTML] Identification of a Novel Functional Non-synonymous Single Nucleotide Polymorphism in Frizzled Class Receptor 6 Gene for Involvement in Depressive …

H Han, M Xu, L Wen, J Chen, Q Liu, J Wang… - Frontiers in molecular …, 2022 - frontiersin.org
Although numerous susceptibility loci for depression have been identified in recent years,
their biological function and molecular mechanism remain largely unknown. By using an …

[HTML][HTML] The higher the household income, the lower the possibility of depression and anxiety disorder: evidence from a bidirectional Mendelian randomization study

G Liu, W Liu, X Zheng, J Li - Frontiers in Psychiatry, 2023 - frontiersin.org
Objectives Observational studies have demonstrated that household income is associated
with morbidity of mental disorders. However, a causal relationship between the two factors …

[HTML][HTML] La depresión mayor en Costa Rica: aspectos epidemiológicos y psicobiológicos

A Sequeira-Cordero, M Blanco-Vargas… - Población y Salud en …, 2022 - scielo.sa.cr
Introducción: la depresión mayor es uno de los trastornos mentales más comunes y una de
las principales causas de discapacidad en el mundo, con una prevalencia que ha …

Local genetic correlation analysis links depression with molecular and brain imaging endophenotypes

J Werme, EP Tissink, SC de Lange… - medRxiv, 2023 - medrxiv.org
Major depressive disorder (MDD) is a heritable psychiatric disorder which is considered one
of the leading causes of disability world-wide. Improved understanding of its genetic …

Gender differences in the association of polygenic risk and divergent depression trajectories from mid to late life: a national longitudinal study

P Chen, Y Li, F Wu - Biodemography and Social Biology, 2023 - Taylor & Francis
Our research fills a critical gap in the depression literature by utilizing a life course
perspective to examine gender–gene interactions in association with depression trajectories …

[PDF][PDF] Depression genetics as a window into physical and mental health

KW Choi - Biological psychiatry, 2022 - Elsevier
Preventing depression and its concomitant health issues is critical to promote healthy aging
and extend lifespan. It is well known that depression and poor health are intertwined (1), but …

Examining the Effect of Genes on Depression as Mediated by Smoking and Modified by Sex

K Voorhies, J Hecker, S Lee, G Hahn, D Prokopenko… - Genes, 2024 - mdpi.com
Depression is heritable, differs by sex, and has environmental risk factors such as cigarette
smoking. However, the effect of single nucleotide polymorphisms (SNPs) on depression …

Development of Artificial Intelligence for Determining Major Depressive Disorder Based on Resting-State EEG and Single-Pulse Transcranial Magnetic Stimulation …

Y Noda, K Sakaue, M Wada, M Takano… - Journal of Personalized …, 2024 - mdpi.com
Depression is the disorder with the greatest socioeconomic burdens. Its diagnosis is still
based on an operational diagnosis derived from symptoms, and no objective diagnostic …

Pre-weaning fluoxetine exposure caused anti-depressant like behavior at adulthood via perturbing tryptophan metabolism in rats

Nadeem, S Usman, R Imad, U Nisar, I Khan… - Metabolic Brain …, 2022 - Springer
The perinatal depression exposes the child to antidepressants during vulnerable window of
development, which can chronically impact the mental wellbeing of new born. Active …

Heritability and polygenic load for combined anxiety and depression.

FF Tabrizi, J Rosen, H Gronvall, V William-Olsson… - medRxiv, 2024 - medrxiv.org
Anxiety and depression commonly occur together resulting in worse health outcomes than
when they occur in isolation. We aimed to determine whether the genetic liability for …