[HTML][HTML] Post-COVID Syndrome in Adults—An Overview

RE Scharf, JM Anaya - Viruses, 2023 - mdpi.com
This article provides an overview of various aspects related to post-COVID syndrome. Apart
from its prevalence, symptoms and sequelae, risk determinants, and psychosocial …

[PDF][PDF] Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity

Y Mitsui, T Suzuki, K Kuniyoshi, J Inamo, K Yamaguchi… - Immunity, 2023 - cell.com
Lung infection during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) via
the angiotensin-I-converting enzyme 2 (ACE2) receptor induces a cytokine storm. However …

[HTML][HTML] Considering innate immune responses in SARS-CoV-2 infection and COVID-19

MS Diamond, JD Lambris, JP Ting… - Nature Reviews …, 2022 - nature.com
During the COVID-19 pandemic, much of the media focus has been on adaptive immunity,
particularly antibody levels and memory T cells. However, immunologists have been striving …

[HTML][HTML] Immune phenotypes that are associated with subsequent COVID-19 severity inferred from post-recovery samples

T Liechti, Y Iftikhar, M Mangino, M Beddall… - Nature …, 2022 - nature.com
Severe COVID-19 causes profound immune perturbations, but pre-infection immune
signatures contributing to severe COVID-19 remain unknown. Genome-wide association …

[HTML][HTML] Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative

G Butler-Laporte, G Povysil, JA Kosmicki… - PLoS …, 2022 - journals.plos.org
Host genetics is a key determinant of COVID-19 outcomes. Previously, the COVID-19 Host
Genetics Initiative genome-wide association study used common variants to identify multiple …

BioSamples database: FAIRer samples metadata to accelerate research data management

M Courtot, D Gupta, I Liyanage, F Xu… - Nucleic acids …, 2022 - academic.oup.com
The BioSamples database at EMBL-EBI is the central institutional repository for sample
metadata storage and connection to EMBL-EBI archives and other resources. The technical …

[PDF][PDF] The HUNT Study: a population-based cohort for genetic research

BM Brumpton, S Graham, I Surakka, AH Skogholt… - Cell Genomics, 2022 - cell.com
Summary The Trøndelag Health Study (HUNT) is a population-based cohort of∼ 229,000
individuals recruited in four waves beginning in 1984 in Trøndelag County, Norway …

Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells

AP Ugalde, G Bretones, D Rodríguez… - The EMBO …, 2022 - embopress.org
Better understanding on interactions between SARS‐CoV‐2 and host cells should help to
identify host factors that may be targetable to combat infection and COVID‐19 pathology. To …

[PDF][PDF] A year of COVID-19 GWAS results from the GRASP portal reveals potential genetic risk factors

F Thibord, MV Chan, MH Chen, AD Johnson - Human Genetics and …, 2022 - cell.com
Host genetic variants influence the susceptibility and severity of several infectious diseases,
and the discovery of genetic associations with coronavirus disease 2019 (COVID-19) …

[HTML][HTML] Integrating single-cell sequencing data with GWAS summary statistics reveals CD16+ monocytes and memory CD8+ T cells involved in severe COVID-19

Y Ma, F Qiu, C Deng, J Li, Y Huang, Z Wu, Y Zhou… - Genome Medicine, 2022 - Springer
Background Understanding the host genetic architecture and viral immunity contributes to
the development of effective vaccines and therapeutics for controlling the COVID-19 …