[HTML][HTML] Adipogenesis: a complex interplay of multiple molecular determinants and pathways

MA Ambele, P Dhanraj, R Giles, MS Pepper - International journal of …, 2020 - mdpi.com
The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …

Adipogenesis: from stem cell to adipocyte

QQ Tang, MD Lane - Annual review of biochemistry, 2012 - annualreviews.org
Excessive caloric intake without a rise in energy expenditure promotes adipocyte
hyperplasia and adiposity. The rise in adipocyte number is triggered by signaling factors that …

TGF-β family signaling in mesenchymal differentiation

I Grafe, S Alexander, JR Peterson… - Cold Spring …, 2018 - cshperspectives.cshlp.org
Mesenchymal stem cells (MSCs) can differentiate into several lineages during development
and also contribute to tissue homeostasis and regeneration, although the requirements for …

Adipocyte differentiation from the inside out

ED Rosen, OA MacDougald - Nature reviews Molecular cell biology, 2006 - nature.com
Improved knowledge of all aspects of adipose biology will be required to counter the
burgeoning epidemic of obesity. Interest in adipogenesis has increased markedly over the …

Adipose tissue dysfunction in obesity, diabetes, and vascular diseases

GR Hajer, TW Van Haeften… - European heart …, 2008 - academic.oup.com
The classical perception of adipose tissue as a storage place of fatty acids has been
replaced over the last years by the notion that adipose tissue has a central role in lipid and …

White fat progenitor cells reside in the adipose vasculature

W Tang, D Zeve, JM Suh, D Bosnakovski, M Kyba… - Science, 2008 - science.org
White adipose (fat) tissues regulate metabolism, reproduction, and life span. Adipocytes
form throughout life, with the most marked expansion of the lineage occurring during the …

[HTML][HTML] Distinction of white, beige and brown adipocytes derived from mesenchymal stem cells

A Park, WK Kim, KH Bae - World journal of stem cells, 2014 - ncbi.nlm.nih.gov
Adipose tissue is a major metabolic organ, and it has been traditionally classified as either
white adipose tissue (WAT) or brown adipose tissue (BAT). WAT and BAT are characterized …

[HTML][HTML] Skeletal muscle insulin resistance: role of mitochondria and other ROS sources

S Di Meo, S Iossa, P Venditti - Journal of Endocrinology, 2017 - joe.bioscientifica.com
Diabetic nephropathy (DN) is the most common cause of end-stage kidney disease
worldwide, and is associated with increased morbidity and mortality in patients with both …

New developments in adipogenesis

MI Lefterova, MA Lazar - Trends in Endocrinology & Metabolism, 2009 - cell.com
The obesity epidemic has focused attention on adipose tissue and the development of fat
cells (ie adipocytes), which is known as adipogenesis. Peroxisome proliferator-activated …

The potential of adipose stem cells in regenerative medicine

B Lindroos, R Suuronen, S Miettinen - Stem Cell Reviews and Reports, 2011 - Springer
Adipose stem cells (ASCs) are an attractive and abundant stem cell source with therapeutic
applicability in diverse fields for the repair and regeneration of acute and chronically …