Sepsis and septic shock are syndromes of immense clinical importance. Suspected sepsis
accounts for more than half a million emergency department visits annually in the United …

In the last 30 years clinical research in the atrial fibrillation (AF) field has seen a great
advance both in terms of productivity and heterogeneity of areas that developed significant …

Background Little attention has focused on the integration of mobile health (mHealth)
technology with self-management approaches to improve the detection and management of …

Randomized data suggest lenient rate control (resting heart rate< 110 beats/min) is
noninferior to strict rate control (resting heart rate< 80 beats/min) in patients with atrial …

Background Conflicting international guidelines exist on the management of sore throat by
antibiotics. Objectives To assess with the Appraisal of Guidelines for Research and …

Background: The objective of this study was to evaluate the evidence-base supporting the
American Heart Association and American College of Cardiology guidelines on peripheral …

Background: The publication rate of neurosurgical guidelines has increased tremendously
over the past decade; however, only a small proportion of clinical decisions appear to be …

Attention to health care quality and safety has increased dramatically. The internal focus of
an organization is not without influence from external policy and research findings …

Background We evaluated the safety and rhythm control effectiveness in en bloc isolation of
the left pulmonary vein (PV) and appendage conducted as part of the thoracoscopic …

Optimal clinical decisions should be supported by clinical practice guidelines (CPG) based
on evidence generated from randomized clinical trials (RCT). We aimed to evaluate the …