Application of ligature-induced periodontitis in mice to explore the molecular mechanism of periodontal disease

P Lin, H Niimi, Y Ohsugi, Y Tsuchiya… - International journal of …, 2021 - mdpi.com
Periodontitis is an inflammatory disease characterized by the destruction of the
periodontium. In the last decade, a new murine model of periodontitis has been widely used …

Targeting the renin-angiotensin-aldosterone system in fibrosis

M AlQudah, TM Hale, MP Czubryt - Matrix Biology, 2020 - Elsevier
Fibrosis is characterized by excessive deposition of extracellular matrix components such as
collagen in tissues or organs. Fibrosis can develop in the heart, kidneys, liver, skin or any …

Periodontal tissues are targets for Sars-Cov-2: a post-mortem study

B Fernandes Matuck, M Dolhnikoff… - Journal of oral …, 2021 - Taylor & Francis
Background: The ability of coronavirus SARS-CoV-2 to spread is one of the determinants of
the COVID-19 pandemic status. Until June 2020, global COVID-19 cases surpassed 10 …

A comprehensive guide to the pharmacologic regulation of angiotensin converting enzyme 2 (ACE2), the SARS-CoV-2 entry receptor

M Oz, DE Lorke, N Kabbani - Pharmacology & therapeutics, 2021 - Elsevier
The recent emergence of coronavirus disease-2019 (COVID-19) as a global pandemic has
prompted scientists to address an urgent need for defining mechanisms of disease …

Role of the renin–angiotensin–aldosterone system in bone metabolism

C Mo, J Ke, D Zhao, B Zhang - Journal of bone and mineral metabolism, 2020 - Springer
With the acceleration of population aging, the incidence of osteoporosis has gradually
increased, and osteoporosis and fractures caused by osteoporosis have gradually become …

Multifunctional hydrogel bioscaffolds based on polysaccharide to promote wound healing: A review

C Ding, X Liu, S Zhang, S Sun, J Yang, G Chai… - International Journal of …, 2024 - Elsevier
Various types of skin wounds pose challenges in terms of healing and susceptibility to
infection, which can have a significant impact on physical and mental well-being, and in …

[HTML][HTML] Tissue regeneration effect of betulin via inhibition of ROS/MAPKs/NF-ĸB axis using zebrafish model

T Ouyang, H Yin, J Yang, Y Liu, S Ma - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Betulin is the primary anti-inflammatory component of Betula platyphylla suk. cortex (birch
bark), a time-honored Traditional Chinese Medicine (TCM) for healing trauma and tissue …

Should we be concerned about the association of diabetes mellitus and periodontal disease in the risk of infection by SARS-CoV-2? A systematic review and …

MA Casillas Santana, JA Arreguin Cano, A Dib Kanan… - Medicina, 2021 - mdpi.com
The objective of this article was to conduct a systematic review of the literature to contrast the
existing evidence regarding the relationship between periodontal disease (PD) and …

Affinity Purification and Molecular Characterization of Angiotensin-Converting Enzyme (ACE)-Inhibitory Peptides from Takifugu flavidus

Y Su, S Chen, S Liu, Y Wang, X Chen, M Xu, S Cai… - Marine Drugs, 2023 - mdpi.com
An affinity chromatography filler of CNBr-activated Sepharose 4B-immobilized ACE was
used to purify ACE-inhibitory peptides from Takifugu flavidus protein hydrolysate (< 1 kDa) …

Overexpression of angiotensin-converting enzyme 2 by renin-angiotensin system inhibitors. Truth or myth? A systematic review of animal studies

H Kai, M Kai, H Niiyama, N Okina, M Sasaki… - Hypertension …, 2021 - nature.com
Abstract Angiotensin-converting enzyme 2 (ACE2) protects against organ damage in
hypertension and cardiovascular diseases by counter regulating the renin-angiotensin …