Dyslipidemia, diabetes and atherosclerosis: role of inflammation and ROS-redox-sensitive factors

E Hasheminasabgorji, JC Jha - Biomedicines, 2021 - mdpi.com
The prevalence of diabetes is growing at an alarming rate with increased disability,
morbidity, and often premature mortality because of the various complications of this …

Role of PI3K in the progression and regression of atherosclerosis

Y Zhao, Y Qian, Z Sun, X Shen, Y Cai, L Li… - Frontiers in …, 2021 - frontiersin.org
Phosphatidylinositol 3 kinase (PI3K) is a key molecule in the initiation of signal transduction
pathways after the binding of extracellular signals to cell surface receptors. An intracellular …

A ROS‐Responsive Liposomal Composite Hydrogel Integrating Improved Mitochondrial Function and Pro‐Angiogenesis for Efficient Treatment of Myocardial …

Z Zheng, C Lei, H Liu, M Jiang, Z Zhou… - Advanced …, 2022 - Wiley Online Library
Mitochondrial dysfunction of cardiomyocytes (CMs) has been identified as a significant
pathogenesis of early myocardial infarction (MI). However, only a few agents or strategies …

A Spiky Silver‐Iron Oxide Nanoparticle for Highly Efficient Targeted Photothermal Therapy and Multimodal Imaging of Thrombosis

KX Vazquez‐Prada, SS Moonshi, Y Wu, F Akther… - Small, 2023 - Wiley Online Library
Thrombosis and its complications are responsible for 30% of annual deaths. Limitations of
methods for diagnosing and treating thrombosis highlight the need for improvements …

Antibody-based therapeutics for atherosclerosis and cardiovascular diseases

E Ji, S Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
Cardiovascular disease is the leading cause of death worldwide, and its prevalence is
increasing due to the aging of societies. Atherosclerosis, a type of chronic inflammatory …

Harnessing nanotechnology for cardiovascular disease applications-a comprehensive review based on bibliometric analysis

Z Zheng, S Zhu, M Lv, Z Gu, H Hu - Nano Today, 2022 - Elsevier
Cardiovascular diseases (CVDs) remain the leading cause of health problems worldwide.
Nanotechnology, based on its unique properties, provides novel solutions to the diagnosis …

Molecular and biochemical pathways of catalpol in alleviating diabetes mellitus and its complications

SK Bhattamisra, HM Koh, SY Lim, H Choudhury… - Biomolecules, 2021 - mdpi.com
Catalpol isolated from Rehmannia glutinosa is a potent antioxidant and investigated against
many disorders. This review appraises the key molecular pathways of catalpol against …

NF-κB, A potential therapeutic target in cardiovascular diseases

W Cheng, C Cui, G Liu, C Ye, F Shao… - … Drugs and Therapy, 2023 - Springer
Cardiovascular diseases (CVDs) are the leading cause of death globally. Atherosclerosis is
the basis of major CVDs–myocardial ischemia, heart failure, and stroke. Among numerous …

The TWEAK/Fn14/CD163 axis—implications for metabolic disease

W Ratajczak, SD Atkinson, C Kelly - Reviews in Endocrine and Metabolic …, 2022 - Springer
TWEAK (tumor necrosis factor-like weak inducer of apoptosis) is a member of the TNF
superfamily that controls a multitude of cellular events including proliferation, migration …

[HTML][HTML] Lipid oxidation in pathophysiology of atherosclerosis: Current understanding and therapeutic strategies

R Salekeen, AN Haider, F Akhter, MM Billah… - International Journal of …, 2022 - Elsevier
A marked increase in the global prevalence of ischemic heart disease demands focused
research for novel and more effective therapeutic strategies. At present, atherosclerotic …