Host defense against viral pathogens is an essential function for all living organisms. In cell-
intrinsic innate immunity, dedicated sensor proteins recognize molecular signatures of …

The α-Klotho protein (henceforth denoted Klotho) has antiaging properties, as first observed
in mice homozygous for a hypomorphic Klotho gene (kl/kl). These mice have a shortened …

Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …

Liver cancer, a result of multifactorial interplay between heredity and the environment, is one
of the leading causes of cancer-related death worldwide. Hepatocellular carcinoma (HCC) is …

The human gut microbiota are critical for preserving the health status because they are
required for digestion and nutrient acquisition, the development of the immune system, and …

CCDC (coiled-coil domain-containing) is a coiled helix domain that exists in natural proteins.
There are about 180 CCDC family genes, encoding proteins that are involved in intercellular …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown diverse life-
threatening effects, most of which are considered short-term. In addition to its short-term …

Sex is known to be an important factor in the incidence, progression, and outcome of cancer.
A better understanding of the underlying mechanisms could help improve cancer prevention …

Lung cancer has the highest incidence of morbidity and mortality throughout the globe. A
large number of patients are diagnosed with lung cancer at the later stages of the disease …

The cancer is a serious health problem, which is The cancer death rate (cancer mortality) is
158.3 per 100,000 men and women per year (based on 2013–2017 deaths). Both clinical …