[HTML][HTML] Novel modified probiotic gold nanoparticles loaded with ginsenoside CK exerts an anti-inflammation effect via NF-κB/MAPK signaling pathways

S Kim, R Wang, S Dhandapani, K Kang, IH Cho… - Arabian Journal of …, 2024 - Elsevier
Abstract Background Gold nanoparticles (AuNPs) exhibit promising potential as medical
materials due to their high biocompatibility, tunable size and shape, and excellent drug …

CD146, a therapeutic target involved in cell plasticity

Z Wu, Y Zang, C Li, Z He, J Liu, Z Du, X Ma… - Science China Life …, 2024 - Springer
Since its identification as a marker for advanced melanoma in the 1980s, CD146 has been
found to have multiple functions in both physiological and pathological processes, including …

NF-κB in the Radiation Response of A549 Non-Small Cell Lung Cancer Cells to X-rays and Carbon Ions under Hypoxia

H Nisar, PM Sanchidrián González… - International journal of …, 2024 - mdpi.com
Cellular hypoxia, detectable in up to 80% of non-small cell lung carcinoma (NSCLC) tumors,
is a known cause of radioresistance. High linear energy transfer (LET) particle radiation …

Cancer-Preventive Activity of Argemone mexicana Linn Leaves and Its Effect on TNF-α and NF-κB Signalling

S Kulshrestha, A Goel, NJ Siddiqi, S Fatima, B Sharma - Cancers, 2023 - mdpi.com
Simple Summary Argemone mexicana is a plant with evidence of traditional use for skin
ailments including infection, psoriasis and cancer. The ethanolic extract was administered to …

Genetic Determinants of Selenium Availability, Selenium-Response, and Risk of Polycystic Ovary Syndrome

P Sharma, P Khetarpal - Biological Trace Element Research, 2024 - Springer
Selenium is a trace element and its deficiency has been associated with the risk of PCOS, a
multifactorial syndrome that affects a large number of women worldwide. Several databases …

Synthesis, Pharmacological Properties, and Potential Molecular Mechanisms of Antitumor Activity of Betulin and Its Derivatives in Gastrointestinal Cancers

M Madej, J Gola, E Chrobak - Pharmaceutics, 2023 - mdpi.com
Gastrointestinal (GI) cancers are an increasingly common type of malignancy, caused by the
unhealthy lifestyles of people worldwide. Limited methods of treatment have prompted the …

Cytokine Signaling in Pediatric Kidney Tumor Cell Lines WT-CLS1, WT-3ab and G-401

E Fasler-Kan, M Milošević, S Ruggiero, N Aliu… - International journal of …, 2024 - mdpi.com
Renal tumors comprise~ 7% of all malignant pediatric tumors. Approximately 90% of
pediatric kidney tumors comprise Wilms tumors, and the remaining 10% include clear cell …

N-Ethyl-N-Nitrosourea Induced Leukaemia in a Mouse Model: Protective Effect of Icaritin via Inhibition of IL-6/JAK2/STAT3 Pathway Causes Apoptosis

X Hou, Y Han, AH Hirad, AA Alarfaj… - Journal of Inflammation …, 2024 - Taylor & Francis
Background The present study aimed to investigate the protective effect of icaritin (ICT) on
ENU-induced leukemia in male mice. Methods The mice received intraperitoneal injections …

The multiple faces of nitric oxide in chronic granulomatous disease: A comprehensive update

JA Garay, JE Silva, MS Di Genaro, RC Davicino - Biomedicines, 2022 - mdpi.com
Nitric oxide (NO), a signaling molecule, regulates multiple biological functions, including a
variety of physiological and pathological processes. In this regard, NO participates in …

[PDF][PDF] Dex-Benchmark: datasets and code to evaluate algorithms for transcriptomics data analysis

Z Xie, C Chen, A Ma'ayan - PeerJ, 2023 - peerj.com
Many tools and algorithms are available for analyzing transcriptomics data. These include
algorithms for performing sequence alignment, data normalization and imputation …