[HTML][HTML] Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Medicinal Fungus Cordyceps with Its Nutraceutical and …

SA Ashraf, AEO Elkhalifa, AJ Siddiqui, M Patel… - Molecules, 2020 - mdpi.com
Cordyceps is a rare naturally occurring entomopathogenic fungus usually found at high
altitudes on the Himalayan plateau and a well-known medicinal mushroom in traditional …

[HTML][HTML] Research progress in the molecular mechanisms, therapeutic targets, and drug development of idiopathic pulmonary fibrosis

H Ma, X Wu, Y Li, Y Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease. Recent studies have
identified the key role of crosstalk between dysregulated epithelial cells, mesenchymal …

Molecular targets in pulmonary fibrosis: the myofibroblast in focus

CJ Scotton, RC Chambers - Chest, 2007 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is one of a group of interstitial lung diseases that are
characterized by excessive matrix deposition and destruction of the normal lung …

[HTML][HTML] Targeting growth factor and cytokine pathways to treat idiopathic pulmonary fibrosis

H Ma, S Liu, S Li, Y Xia - Frontiers in Pharmacology, 2022 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease of unknown origin
that usually results in death from secondary respiratory failure within 2–5 years of diagnosis …

PPAR-γ agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis

JE Milam, VG Keshamouni, SH Phan… - … of Physiology-Lung …, 2008 - journals.physiology.org
Pulmonary fibrosis is characterized by alterations in fibroblast phenotypes resulting in
excessive extracellular matrix accumulation and anatomic remodeling. Current therapies for …

Idiopathic pulmonary fibrosis: outcome in relation to smoking status

KM Antoniou, DM Hansell, MB Rubens… - American journal of …, 2008 - atsjournals.org
Rationale: The pathogenic importance of smoking status in idiopathic pulmonary fibrosis
(IPF) is uncertain. In theory, increased oxidative stress in current and former smokers might …

Molecular pathways and role of epigenetics in the idiopathic pulmonary fibrosis

V Velagacherla, CH Mehta, Y Nayak, UY Nayak - Life Sciences, 2022 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease with unknown etiological factors
that can progress to other dangerous diseases like lung cancer. Environmental and genetic …

[HTML][HTML] Periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis

SL Ashley, CA Wilke, KK Kim, BB Moore - Mucosal immunology, 2017 - Elsevier
Fibrocytes are circulating mesenchymal precursors (CD45+, col 1+) recruited to fibrotic
areas. Fibrocytes secrete profibrotic mediators including periostin; a matricellular protein that …

Apoptosis in lung injury and fibrosis

F Drakopanagiotakis, A Xifteri… - European …, 2008 - Eur Respiratory Soc
Pulmonary fibrosis is characterised by fibroblast accumulation and alveolar epithelium
denudation. Increased apoptosis of alveolar epithelial cells and decreased apoptosis of …

Timosaponin BII inhibits TGF‐β mediated epithelial‐mesenchymal transition through Smad‐dependent pathway during pulmonary fibrosis

D Ding, X Shen, L Yu, Y Zheng, Y Liu… - Phytotherapy …, 2023 - Wiley Online Library
Pulmonary fibrosis (PF) is a progressive and fatal interstitial lung disease with limited
therapeutic options at present, and epithelial–mesenchymal transition (EMT) is recognized …