COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection

S Beyerstedt, EB Casaro, ÉB Rangel - European journal of clinical …, 2021 - Springer
COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Angiotensin-
converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell …

COVID-19, myocarditis and pericarditis

DL Fairweather, DJ Beetler, DN Di Florio… - Circulation …, 2023 - Am Heart Assoc
Viral infections are a leading cause of myocarditis and pericarditis worldwide, conditions that
frequently coexist. Myocarditis and pericarditis were some of the early comorbidities …

COVID-19 transmission, current treatment, and future therapeutic strategies

VS Salian, JA Wright, PT Vedell, S Nair… - Molecular …, 2021 - ACS Publications
At the stroke of the New Year 2020, COVID-19, a zoonotic disease that would turn into a
global pandemic, was identified in the Chinese city of Wuhan. Although unique in its …

Pathophysiological mechanisms of liver injury in COVID‐19

AD Nardo, M Schneeweiss‐Gleixner… - Liver …, 2021 - Wiley Online Library
The recent outbreak of coronavirus disease 2019 (COVID‐19), caused by the Severe Acute
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) has resulted in a world‐wide …

Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

AR Bourgonje, AE Abdulle, W Timens… - The Journal of …, 2020 - Wiley Online Library
Abstract Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional
host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …

Potential intestinal infection and faecal–oral transmission of SARS-CoV-2

M Guo, W Tao, RA Flavell, S Zhu - Nature reviews Gastroenterology & …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …

Extrapulmonary manifestations of COVID-19

A Gupta, MV Madhavan, K Sehgal, N Nair… - Nature medicine, 2020 - nature.com
Although COVID-19 is most well known for causing substantial respiratory pathology, it can
also result in several extrapulmonary manifestations. These conditions include thrombotic …

Shedding of SARS-CoV-2 in feces and urine and its potential role in person-to-person transmission and the environment-based spread of COVID-19

DL Jones, MQ Baluja, DW Graham, A Corbishley… - Science of the Total …, 2020 - Elsevier
The recent detection of SARS-CoV-2 RNA in feces has led to speculation that it can be
transmitted via the fecal-oral/ocular route. This review aims to critically evaluate the …

HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry

C Wei, L Wan, Q Yan, X Wang, J Zhang, X Yang… - Nature …, 2020 - nature.com
Responsible for the ongoing coronavirus disease 19 (COVID-19) pandemic, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through binding of the …

SARS-CoV-2 tropism, entry, replication, and propagation: Considerations for drug discovery and development

N Murgolo, AG Therien, B Howell, D Klein… - Advances in Clinical …, 2021 - taylorfrancis.com
Coronaviruses, named for their crown-like spiked surface, are genetically diverse and can
infect multiple animal species, including bats, pigs, cats, rodents, and humans. Aside from …