Construction of prognostic risk model of 5-methylcytosine-related long non-coding RNAs and evaluation of the characteristics of tumor-infiltrating immune cells in …

Z Huang, J Li, J Chen, D Chen - Frontiers in Genetics, 2021 - frontiersin.org
Purpose: The role of 5-methylcytosine-related long non-coding RNAs (m5C-lncRNAs) in
breast cancer (BC) remains unclear. Here, we aimed to investigate the prognostic value …

[HTML][HTML] Non-coding RNAs regulating epithelial-mesenchymal transition: Research progress in liver disease

X Yang, Z Jiang, Y Li, Y Zhang, Y Han, L Gao - Biomedicine & …, 2022 - Elsevier
Chronic liver injury could gradually progress to liver fibrosis, cirrhosis, and even hepatic
carcinoma without effective treatment. The massive production and activation of abnormal …

METTL3/14 and IL‐17 signaling contribute to CEBPA‐DT enhanced oral cancer cisplatin resistance

X Qiao, L Zhu, R Song, C Shang, Y Guo - Oral Diseases, 2023 - Wiley Online Library
Objectives Oral squamous cell carcinoma (OSCC) is the most common head and neck
cancer. Chemotherapy has been recognized as an optional combination treatment, which …

METTL3 facilitates multiple myeloma tumorigenesis by enhancing YY1 stability and pri-microRNA-27 maturation in m6A-dependent manner

F Che, X Ye, Y Wang, X Wang, S Ma, Y Tan… - Cell Biology and …, 2023 - Springer
Multiple myeloma (MM) is a pernicious plasma cell disorder and has a poor prognosis. N 6-
methyladenosine (m6A) is an abundant epigenetic RNA modification and is important in …

M6A-related lncRNAs predict clinical outcome and regulate the tumor immune microenvironment in hepatocellular carcinoma

B Chen, Z Yang, Z Lang, Q Tao, R Zhang, Y Zhan, X Xu… - BMC cancer, 2022 - Springer
Abstract LncRNA N6-methylandenosine (m6A) modification has been shown to be
associated with the constitution of the tumor microenvironment (TME) and tumorigenesis. It's …

ebv-circRPMS1 promotes the progression of EBV-associated gastric carcinoma via Sam68-dependent activation of METTL3

J Zhang, Y Du, L Gong, Y Shao, L Pan, Z Feng, Y Pan… - Cancer Letters, 2022 - Elsevier
Epstein–Barr virus (EBV) is a tumor virus that is associated with a variety of neoplasms,
including EBV-associated gastric carcinoma (EBVaGC). Recently, EBV was reported to …

m6A demethylation of cytidine deaminase APOBEC3B mRNA orchestrates arsenic-induced mutagenesis

M Gao, Z Qi, W Feng, H Huang, Z Xu, Z Dong… - Journal of Biological …, 2022 - ASBMB
The cytidine deaminase APOBEC3B (A3B) is an endogenous inducer of somatic mutations
and causes chromosomal instability by converting cytosine to uracil in single-stranded DNA …

LncRNA HCG11 mediated by METTL14 inhibits the growth of lung adenocarcinoma via IGF2BP2/LATS1

J Mao, H Qiu, L Guo - Biochemical and biophysical research …, 2021 - Elsevier
Lung adenocarcinoma (LUAD) is a common malignancy the pathogenesis of which is
terribly complicated and remains largely unclear. Long non-coding RNAs (lncRNAs) are a …

METTL3-mediated long non-coding RNA MIR99AHG methylation targets miR-4660 to promote bone marrow mesenchymal stem cell osteogenic differentiation

L Li, B Wang, X Zhou, H Ding, C Sun, Y Wang… - Cell Cycle, 2023 - Taylor & Francis
Whether long non-coding RNA Mir-99a-Let-7c Cluster Host Gene (LncRNA MIR99AHG) is
involved in osteoporosis (OP) remains vague, so we hereby center on its implication. Old …

Comprehensive analysis of tumor immune microenvironment and prognosis of m6A-related lncRNAs in gastric cancer

Y Wang, GQ Zhu, D Tian, CW Zhou, N Li, Y Feng… - BMC cancer, 2022 - Springer
Abstract Background N6-methyladenosine (m6A) modification and long non-coding RNAs
(lncRNAs) play pivotal roles in gastric cancer (GC) progression. The emergence of …