Polysaccharide-based platforms for nasal delivery: design, features, and perspectives

E Elmowafy, ME Soliman - Journal of Pharmaceutical Investigation, 2023 - Springer
Background Polysaccharides acceded by the Food and Drug Administration are among the
most exploitable polymers for fabricating nasally applied vehicles containing therapeutically …

A review on recent upgradation and strategies to enhance cyclodextrin glucanotransferase properties for its applications

K Rabadiya, D Pardhi, K Thaker, J Patoliya… - International Journal of …, 2024 - Elsevier
Cyclodextrin glycosyltransferase (CGTase) is a significant extracellular enzyme with diverse
functions. CGTase is widely used in production of cyclic α-(1, 4)-linked oligosaccharides …

[HTML][HTML] Co-Delivery of a High Dose of Amphotericin B and Itraconazole by Means of a Dry Powder Inhaler Formulation for the Treatment of Severe Fungal Pulmonary …

SS Celi, R Fernández-García, AI Afonso-Urich… - Pharmaceutics, 2023 - mdpi.com
Over the past few decades, there has been a considerable rise in the incidence and
prevalence of pulmonary fungal infections, creating a global health problem due to a lack of …

[HTML][HTML] Cyclodextrin in vaccines: enhancing Efficacy and Stability

G Varan - Future Pharmacology, 2023 - mdpi.com
Cyclodextrins, a family of cyclic oligosaccharides, have received considerable interest in the
field of pharmaceuticals due to their unique molecular structure and versatile properties. In …

A micro-fabricated potentiometric platform with application in a COVID-19 drug quantification and the determination of its binding affinity to a supramolecular host

NB El Din, NM Ali, MK Abd El-Rahman, T Shoeib - Microchemical Journal, 2024 - Elsevier
Recent applications in host–guest chemistry include advanced sensing technologies, drug
formulations, and drug delivery. Quantification of host–guest binding constants is significant …

[HTML][HTML] Cyclodextrins as building blocks for new materials

M Kfoury, S Fourmentin - Beilstein Journal of Organic …, 2023 - beilstein-journals.org
The continuous increase in the number of publications carried out on cyclodextrins (CDs)
and their market growth are clear evidence of the undying interest in these macrocycles …

Cyclodextrins and their potential applications for delivering vitamins, iron, and iodine for improving micronutrient status

S Saffarionpour, LL Diosady - Drug Delivery and Translational Research, 2024 - Springer
Cyclodextrins (CDs) have been investigated as potential biopolymeric carriers that can form
inclusion complexes with numerous bioactive ingredients. The inclusion of micronutrients …

Super porous α‐, β‐, γ‐cyclodextrin cryogels with high active agent loading and controllable release profiles

AS Yilmaz, N Sahiner - Journal of Applied Polymer Science, 2024 - Wiley Online Library
Cyclodextrins (CDs) are truncated cone‐like structures that are natural cyclic
oligosaccharides. Here, a simple preparation method for super porous poly (α‐CD), poly (β …

Molecular insights to the anti-COVID-19 potential of α-, β-and γ-cyclodextrins

V Kumar, HN Meidinna, SC Kaul, D Gupta… - Journal of …, 2023 - Taylor & Francis
SARS-CoV-2 viral infection is regulated by the host cell receptors ACE2 and TMPRSS2, and
therefore the effect of various natural and synthetic compounds on these receptors has …

[HTML][HTML] Host–Guest Complexation of Itraconazole with Cyclodextrins for Bioavailability Enhancement

LM Şuta, A Ridichie, A Ledeţi, C Temereancă, I Ledeţi… - Pharmaceutics, 2024 - mdpi.com
Itraconazole is an antifungal agent included in the triazole pharmacological classification
that belongs to the BCS class II, characterized by a low solubility in an aqueous medium (of …