Urine as a source of liquid biopsy for cancer

M Oshi, V Murthy, H Takahashi, M Huyser, M Okano… - Cancers, 2021 - mdpi.com
Simple Summary Tissue biopsy is essential for diagnosis and characterization of a tumor.
Recently circulating tumor cells and other tumor-derived nucleic acid can be detected from …

[HTML][HTML] Long non-coding RNAs in anti-cancer drug resistance

Q Chen, C Wei, Z Wang, M Sun - Oncotarget, 2017 - ncbi.nlm.nih.gov
Chemotherapy is one of the basic treatments for cancers; however, drug resistance is mainly
responsible for the failure of clinical treatment. The mechanism of drug resistance is …

Long non-coding RNAs: key regulators of epithelial-mesenchymal transition, tumour drug resistance and cancer stem cells

R Heery, SP Finn, S Cuffe, SG Gray - Cancers, 2017 - mdpi.com
Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …

[HTML][HTML] circPTCH1 promotes invasion and metastasis in renal cell carcinoma via regulating miR-485-5p/MMP14 axis

H Liu, G Hu, Z Wang, Q Liu, J Zhang, Y Chen… - Theranostics, 2020 - ncbi.nlm.nih.gov
Background: Circular RNAs (circRNAs) are a new class of non-coding RNAs (ncRNAs) that
are derived from exons or introns by special selective shearing. circRNAs have been shown …

Long non‐coding RNAs in cancer: another layer of complexity

JC de Oliveira, LC Oliveira, C Mathias… - The journal of gene …, 2019 - Wiley Online Library
We review the most well characterized long non‐coding RNAs (lncRNAs) with important
roles in hallmarks of cancer, additionally including lncRNAs with a higher potential for …

Regulatory roles of long noncoding RNAs implicated in cancer hallmarks

J Wang, X Zhang, W Chen, X Hu, J Li… - International journal of …, 2020 - Wiley Online Library
Cancer cells acquire numerous biological properties (designated “cancer hallmarks”), such
as cell survival and energy metabolism, that facilitate tumor growth and metastatic …

Downregulation of lncRNA UCA1 ameliorates the damage of dopaminergic neurons, reduces oxidative stress and inflammation in Parkinson's disease through the …

L Cai, LI Tu, T Li, X Yang, Y Ren, R Gu, Q Zhang… - International …, 2019 - Elsevier
This study is conducted to investigate the role of lncRNA urothelial carcinoma-associated 1
(UCA1) in the protection of dopaminergic neurons in Parkinson's disease (PD) through …

Role of lncRNAs in ovarian cancer: defining new biomarkers for therapeutic purposes

MK Tripathi, K Doxtater, F Keramatnia, C Zacheaus… - Drug Discovery …, 2018 - Elsevier
Highlights•New roles of lncRNAs in ovarian cancer biology.•lncRNA as new prognostic
biomarkers for ovarian cancer patients.•Role of lncRNA in metastasis, recurrence and drug …

The lnc RNA MALAT 1 functions as a competing endogenous RNA to regulate MCL‐1 expression by sponging miR‐363‐3p in gallbladder cancer

SH Wang, WJ Zhang, XC Wu, MZ Weng… - Journal of cellular …, 2016 - Wiley Online Library
Gallbladder carcinoma (GBC) is an aggressive neoplasm, and the treatment options for
advanced GBC are limited. Recently, long non‐coding RNA s (lnc RNA s) have emerged as …

[HTML][HTML] Overexpression of lncRNA UCA1 promotes osteosarcoma progression and correlates with poor prognosis

W Li, P Xie, W Ruan - Journal of bone oncology, 2016 - Elsevier
Long non-coding RNAs (lncRNAs) have been proved to play important roles in the
tumorigenesis and development of several human malignancies. Our study aims to …