Neurobiology and systems biology of stress resilience

R Kalisch, SJ Russo, MB Müller - Physiological Reviews, 2024 - journals.physiology.org
Stress resilience is the phenomenon that some people maintain their mental health despite
exposure to adversity or show only temporary impairments followed by quick recovery …

Childhood trauma and epigenetics: state of the science and future

N Gladish, SM Merrill, MS Kobor - Current Environmental Health Reports, 2022 - Springer
Abstract Purpose of Review There is a great deal of interest regarding the biological
embedding of childhood trauma and social exposures through epigenetic mechanisms …

[HTML][HTML] Associations between plasma inflammatory markers and psychotic disorder, depressive disorder and generalised anxiety disorder in early adulthood: A …

D Mongan, SR Susai, M Föcking, JF Byrne… - Brain, Behavior, and …, 2023 - Elsevier
Background Low-grade inflammation may occur in association with several mental disorders
of early adulthood, though associations with markers of chronic inflammation such as …

[HTML][HTML] Exposure to childhood maltreatment and systemic inflammation across pregnancy: The moderating role of depressive symptomatology

TS Kleih, S Entringer, L Scholaske, N Kathmann… - Brain, behavior, and …, 2022 - Elsevier
Background Childhood maltreatment (CM) has long-term consequences for dysregulation of
the immune system which is particularly pronounced when mental and physical health …

[HTML][HTML] Association between childhood trauma and Internet gaming disorder: a moderated mediation analysis with depression as a mediator and psychological …

Q Liu, L Ouyang, L Fan, A Liao, Z Li, X Chen, L Yuan… - BMC psychiatry, 2024 - Springer
Background The effect of childhood trauma on Internet gaming disorder remains unclear. In
this study, we examined this association in Chinese students and explored the possible …

[HTML][HTML] Inflammation as a mediator between adverse childhood experiences and adult depression: A meta-analytic structural equation model

A Zagaria, V Fiori, M Vacca, C Lombardo… - Journal of Affective …, 2024 - Elsevier
Exposure to adverse childhood experiences (ACEs) confers a higher risk of developing
depression in adulthood, yet the mediation of inflammation remains under debate. To test …

[HTML][HTML] Childhood trauma and LPS-stimulated inflammation in adulthood: Results from the Netherlands Study of Depression and Anxiety

RM de Koning, E Kuzminskaite, CH Vinkers… - Brain, behavior, and …, 2022 - Elsevier
Background Childhood trauma (CT) is robustly associated with psychiatric disorders
including major depressive and anxiety disorders across the life span. The innate immune …

[HTML][HTML] Inflammation and cognitive performance in first-episode schizophrenia spectrum disorders: The moderating effects of childhood trauma

B Keřková, K Knížková, M Večeřová, P Šustová… - Schizophrenia …, 2023 - Elsevier
In this study, we aimed to determine whether childhood trauma moderated the relationship
between inflammation and cognitive functioning in persons with first-episode schizophrenia …

[HTML][HTML] Subcutaneous Mycobacterium vaccae ameliorates the effects of early life adversity alone or in combination with chronic stress during adulthood in male and …

G Mazzari, CA Lowry, D Langgartner, SO Reber - Neurobiology of Stress, 2023 - Elsevier
Chronic psychosocial stress is a burden of modern society and poses a clear risk factor for a
plethora of somatic and affective disorders, of which most are associated with an activated …

[HTML][HTML] Inflammatory mediators in major depression and bipolar disorder

S Poletti, MG Mazza, F Benedetti - Translational Psychiatry, 2024 - nature.com
Major depressive disorder (MDD) and bipolar disorder (BD) are highly disabling illnesses
defined by different psychopathological, neuroimaging, and cognitive profiles. In the last …