Research Progress on Injectable Microspheres as New Strategies for the Treatment of Osteoarthritis Through Promotion of Cartilage Repair

J Lin, S Jia, F Cao, J Huang, J Chen… - Advanced Functional …, 2024 - Wiley Online Library
Osteoarthritis (OA) is a degenerative disease caused by a variety of factors with joint pain as
the main symptom, including fibrosis, chapping, ulcers, and loss of cartilage. Traditional …

Molecular biomarker approaches to prevention of post-traumatic osteoarthritis

VB Kraus, MF Hsueh - Nature Reviews Rheumatology, 2024 - nature.com
Up to 50% of individuals develop post-traumatic osteoarthritis (PTOA) within 10 years
following knee-joint injuries such as anterior cruciate ligament rupture or acute meniscal …

Endothelial Stat3 activation promotes osteoarthritis development

J Li, W Zhang, X Liu, G Li, Y Gu, K Zhang… - Cell …, 2023 - Wiley Online Library
The mechanism of the balance between subchondral angiogenesis and articular damage
within osteoarthritis (OA) progression remains a mystery. However, the lack of specific drugs …

Evaluating the potential of Vitamin D and curcumin to alleviate inflammation and mitigate the progression of osteoarthritis through their effects on human chondrocytes …

R Patnaik, S Riaz, BM Sivani, S Faisal, N Naidoo… - Plos one, 2023 - journals.plos.org
Osteoarthritis (OA) is a chronic degenerative joint disorder primarily affecting the elderly,
characterized by a prominent inflammatory component. The long-term side effects …

Comprehensive Review on the Virulence Factors and Therapeutic Strategies with the Aid of Artificial Intelligence against Mucormycosis

M Tanwar, A Singh, TP Singh, S Sharma… - ACS Infectious …, 2024 - ACS Publications
Mucormycosis, a rare but deadly fungal infection, was an epidemic during the COVID-19
pandemic. The rise in cases (COVID-19-associated mucormycosis, CAM) is attributed to …

Intra‐Articular Injection of Nanomaterials for the Treatment of Osteoarthritis: From Lubrication Function Restoration to Cell and Gene Therapy

Y Yang, H Zhang - Advanced Functional Materials, 2024 - Wiley Online Library
Osteoarthritis (OA), a prevalent joint disease affecting many people globally, presents
significant challenge in current treatments, which often only manage symptoms without …

Emerging technology has a brilliant future: the CRISPR-Cas system for senescence, inflammation, and cartilage repair in osteoarthritis

S Jia, R Liang, J Chen, S Liao, J Lin, W Li - Cellular & Molecular Biology …, 2024 - Springer
Osteoarthritis (OA), known as one of the most common types of aseptic inflammation of the
musculoskeletal system, is characterized by chronic pain and whole-joint lesions. With …

Elucidation of the key therapeutic targets and potential mechanisms of Andrographolide multi-targets against osteoarthritis via network pharmacological analysis and …

T Yang, T Cao, X Yang, G Wang, Y Li - Gene, 2024 - Elsevier
Objective Our purpose is to unveil Andrographolide's potential multi-target and multi-
mechanism therapeutic effects in treating OA via systematic network pharmacological …

[HTML][HTML] curculigoside inhibits osteoarthritis via the regulation of NLrP3 pathway

X Wang, Y Liu, Y Zhou, Y Zhou, Y Li - European Journal of …, 2023 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is characterized by degenerative articular cartilage. Nucleotide-binding
oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) plays an important …