Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus (SARS-CoV)-2, continues to cause substantial morbidity …

Acute pancreatitis is a common indication for hospital admission, increasing in incidence,
including in children, pregnancy and the elderly. Moderately severe acute pancreatitis with …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for
coronavirus disease 2019 (COVID-19), continues to cause substantial morbidity and …

The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …

The lungs are constantly exposed to inhaled debris, allergens, pollutants, commensal or
pathogenic microorganisms, and respiratory viruses. As a result, innate and adaptive …

Programmed cell death (PCD) is an essential part of organismal development and plays
fundamental roles in host defense against pathogens and the maintenance of homeostasis …

Pyroptosis, apoptosis and necroptosis are the most genetically well-defined programmed
cell death (PCD) pathways, and they are intricately involved in both homeostasis and …

Alzheimer's disease (AD) is a neurodegenerative disorder molecularly characterized by the
formation of amyloid β (Aβ) plaques and type 2 microtubule-associated protein (Tau) …

Synergistically improving T-cell responsiveness is promising for favorable therapeutic
outcomes in immunologically cold tumors, yet current treatments often fail to induce a …

The innate immune system provides the first line of defense against cellular perturbations.
Innate immune activation elicits inflammatory programmed cell death in response to …