ABSTRACT T cell engaging therapies, like CAR-T cells and T cell engagers, redirect T cells
toward tumor cells, facilitating the formation of a cytotoxic synapse and resulting in …

African swine fever (ASF) is a hemorrhagic viral disease of domestic pigs and wild suids (all
Sus scrofa) caused by the ASF virus (ASFV). The disease is spreading worldwide without …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a contagious respiratory
virus that is the cause of the coronavirus disease 2019 (COVID-19) pandemic which has …

The severe acute respiratory coronavirus 2 (SARS-CoV-2) has become a life-threatening
pandemic. Clinical evidence suggests that kidney involvement is common and might lead to …

Purpose: Target-dependent TCB activity can result in the strong and systemic release of
cytokines that may develop into cytokine release syndrome (CRS), highlighting the need to …

Severity of COVID-19 shows an extraordinary correlation with increasing age. We generated
a mouse model for severe COVID-19 and show that the age-dependent disease severity is …

Immunotherapy aims to activate the cancer patient's immune system for cancer therapy. The
whole process of the immune system against cancer referred to as the “cancer immunity …

Chemotherapeutic drugs have been found to activate the immune response against tumors
by inducing immunogenic cell death, in addition to their direct cytotoxic effects toward …

Abnormal inflammatory mediator concentrations during SARS-CoV-2 infection may
represent disease severity. We aimed to assess plasma inflammatory mediator …

Acute respiratory distress syndrome (ARDS) is a heterogeneous cause of respiratory failure
that has a rapid onset, a high mortality rate, and for which there is no effective …