In this work, we develop mathematical models of the immune response to respiratory viral
infection, taking into account some particular properties of the SARS-CoV infections …

The COVID-19 pandemic, caused by the β-coronavirus (β-CoV) severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), continues to cause significant global morbidity and …

Ovarian cancer is a less common tumor in women compared to cervical or breast cancer,
however it is more malignant and has worse outcomes. Ovarian cancer patients still have a …

Background Lipopolysaccharide, a highly potent endotoxin responsible for severe sepsis, is
the major constituent of the outer membrane of gram-negative bacteria. Endothelial cells …

Acute respiratory distress syndrome (ARDS) is a heterogeneous cause of respiratory failure
that has a rapid onset, a high mortality rate, and for which there is no effective …

We are not entirely able to understand, assess, and modulate the functioning of the immune
system in clinical situations that lead to a systemic inflammatory response. In the search for …

Background and objective Cytokine storm (CS) is a major contributor to the fatal outcome of
severe infectious diseases, including Covid-19. Treatment with the complement (C) C5 …

Filoviruses are a group of single-stranded negative sense RNA viruses. The most well-
known filoviruses that affect humans are ebolaviruses and marburgviruses. During infection …

The term “cytokine storm” describes an acute pathophysiologic state of the immune system
characterized by a burst of cytokine release, systemic inflammatory response, and multiple …

Necroptosis is a form of regulated necrosis mainly controlled by receptor-interacting protein
kinases 3 (RIPK3) and mixed lineage kinase domain-like protein (MLKL). Necroptosis has …