Construction of a machine learning-based artificial neural network for discriminating PANoptosis related subgroups to predict prognosis in low-grade gliomas

GF Chen, ZM He, W Jiang, LL Li, B Luo, XY Wang… - Scientific Reports, 2022 - nature.com
The poor prognosis of gliomas necessitates the search for biomarkers for predicting clinical
outcomes. Recent studies have shown that PANoptosis play an important role in tumor …

Crosstalk of Inflammation and Coagulation in Bothrops Snakebite Envenoming: Endogenous Signaling Pathways and Pathophysiology

JS Cavalcante, DEG de Almeida… - International Journal of …, 2023 - mdpi.com
Snakebite envenoming represents a major health problem in tropical and subtropical
countries. Considering the elevated number of accidents and high morbidity and mortality …

Research progress on the effect of traditional Chinese medicine on the activation of PRRs-mediated NF-κB signaling pathway to inhibit influenza pneumonia

L Zhang, X Ye, Y Liu, Z Zhang, X Xia… - Frontiers in …, 2023 - frontiersin.org
Influenza pneumonia has challenged public health and social development. One of the
hallmarks of severe influenza pneumonia is overproduction of pro-inflammatory cytokines …

Transcriptomic profiling the effects of airway exposure of zinc oxide and silver nanoparticles in mouse lungs

L Zhao, S Wang, M Ilves, S Lehtonen, L Saikko… - International Journal of …, 2023 - mdpi.com
Consumers and manufacturers are exposed to nanosized zinc oxide (nZnO) and silver
particles (nAg) via airways, but their biological effects are still not fully elucidated. To …

Severe systemic inflammation mimicking TAFRO syndrome following COVID-19

M Tane, H Kosako, H Hosoi, K Tabata, T Hiroi… - International Journal of …, 2023 - Springer
TAFRO syndrome is a rare systemic inflammatory disease. Its pathogenesis mainly involves
excessive cytokine secretion and autoimmune dysfunction. Although its etiology is unclear …

IFN-γ promotes PANoptosis in Pasteurella multocida toxin-induced pneumonia in mice

H Xiao, Q Zhao, J Yuan, W Liang, R Wu, Y Wen… - Veterinary …, 2023 - Elsevier
Abstract Interferon-γ (IFN-γ) is a pleiotropic cytokine that regulates diverse biological
functions, including modulation of inflammatory response and innate and adaptive immunity …

Phosphate and IL-10 concentration as predictors of long-covid in hemodialysis patients: A Brazilian study

HL Corrêa, LA Deus, TB Araújo, AL Reis… - Frontiers in …, 2022 - frontiersin.org
Background The global burden of persistent COVID-19 in hemodialysis (HD) patients is a
worrisome scenario worth of investigation for the critical care of chronic kidney disease …

Annao Pingchong decoction alleviate the neurological impairment by attenuating neuroinflammation and apoptosis in intracerebral hemorrhage rats

C Guo, X Zhou, X Wang, H Wang, J Liu, J Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Intracerebral hemorrhage (ICH) is a central nervous
system disease that causes severe disability or death. Even though Annao Pingchong …

Extracellular vesicles in inner ear therapies—pathophysiological, manufacturing, and clinical considerations

A Warnecke, H Staecker, E Rohde, M Gimona… - Journal of Clinical …, 2022 - mdpi.com
(1) Background: Sensorineural hearing loss is a common and debilitating condition. To date,
comprehensive pharmacologic interventions are not available. The complex and diverse …

[PDF][PDF] Whole-genome CRISPR screen identifies RAVER1 as a key regulator of RIPK1-mediated inflammatory cell death, PANoptosis

RKS Malireddi, RR Bynigeri, R Mall, EK Nadendla… - Iscience, 2023 - cell.com
Transforming growth factor-β-activated kinase 1 (TAK1) is a central regulator of innate
immunity, cell death, inflammation, and cellular homeostasis. Therefore, many pathogens …