Sepsis is a serious disease caused by an impaired host immune response to infection,
resulting in organ dysfunction, tissue damage and is responsible for high in-hospital …

The molecular underpinnings of the uncontrolled release of proinflammatory cytokines and
chemokines ('cytokine storm'), which can cause organ damage and even mortality, are not …

ABSTRACT Streptococcus suis type 2 (SS2), a major emerging/re-emerging zoonotic
pathogen found in humans and pigs, can cause severe clinical infections, and pose public …

Severe acute pancreatitis (AP) is a life-threatening pancreatic inflammatory disease with a
high mortality rate (∼ 40%). Existing pharmaceutical therapies in development or in clinical …

Introduction The pathogenesis of Vibrio mimicus infection in yellow catfish (Pelteobagrus
fulvidraco) remains poorly understood, particularly regarding the impact of infection with the …

The immunosuppression hazard of fish brought by intensive aquaculture needs to be
addressed urgently, while chitooligosaccharide (COS) shows the potential application in the …

Abstract Ethnopharmacological relevance Platycodonis Radix (PR) is a traditional herbal
remedy used to prevent and treat lung inflammation, and platycodins are speculated to be …

Type I and III Interferons (IFNs) are the first lines of defense in microbial infections. They
critically block early animal virus infection, replication, spread, and tropism to promote the …

Influenza virus is one of the most common infectious pathogens that could cause high
morbidity and mortality in humans. However, the occurrence of drug resistance and serious …

Background Hyperinflammation is a life-threatening condition associated with various
clinical disorders characterized by excessive immune activation and tissue damage. Multiple …