Ageing is a global burden. Increasing age is associated with increased incidence of
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …

Purpose: Central retinal artery occlusion (CRAO) is a form of acute ischemic stroke that
causes severe visual loss and is a harbinger of further cerebrovascular and cardiovascular …

Objective To provide evidence‐based recommendations and expert guidance for the
management of giant cell arteritis (GCA) and Takayasu arteritis (TAK) as exemplars of large …

Background GCA is a large vessel vasculitis affecting older people, with the highest
incidence among persons 70–79 years of age [1]. Due to forecasted demographic changes …

Background Giant cell arteritis is an immune-mediated disease of medium and large-sized
arteries that affects mostly people older than 50 years of age. Treatment with glucocorticoids …

Importance High-flow nasal oxygen therapy is increasingly used for acute hypoxemic
respiratory failure (AHRF). Objective To determine whether high-flow oxygen therapy …

Importance Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are related
inflammatory disorders occurring in persons aged 50 years and older. Diagnostic and …

Polymyalgia rheumatica is an inflammatory disease that affects the shoulder, the pelvic
girdles, and the neck, usually in individuals older than 50 years. Increases in acute phase …

Objective To compare the efficacy of abatacept to that of placebo for the treatment of giant
cell arteritis (GCA). Methods In this multicenter trial, patients with newly diagnosed or …

The immune systems of post-pubescent males and females differ significantly with profound
consequences to health and disease. In many cases, sex-specific differences in the immune …