[HTML][HTML] Autophagy-related lncRNAs in tumor progression and drug resistance: a double-edged sword

Y Zhang, J Tang, C Wang, Q Zhang, A Zeng, L Song - Genes & Diseases, 2024 - Elsevier
The incidence and mortality rates of cancer are increasing every year worldwide but the
survival rate of cancer patients is still unsatisfactory. Therefore, it is necessary to further …

[HTML][HTML] Epigenetic regulation of temozolomide resistance in human cancers with an emphasis on brain tumors: Function of non-coding RNAs

A Rezaee, PM Tehrany, FJ Tirabadi, N Sanadgol… - Biomedicine & …, 2023 - Elsevier
Brain tumors, which are highly malignant, pose a significant threat to health and often result
in substantial rates of mortality and morbidity worldwide. The brain cancer therapy has been …

Cancer-associated fibroblasts suppressed ferroptosis in glioblastoma via upregulating lncRNA DLEU1

J Zhao, S Yang, C Lv, Y Liu - American Journal of …, 2023 - journals.physiology.org
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults. It is
crucial to elucidate the mechanism underlying ferroptosis resistance in GBM. We used qRT …

Discovery and validation of clinically relevant long non-coding RNAs in colorectal cancer

M Snyder, S Iraola-Guzman, E Saus, T Gabaldon - Cancers, 2022 - mdpi.com
Simple Summary Recent efforts in biomedical research have focused on the identification of
molecular biomarkers to improve the diagnosis, prognosis and eventually treatment of the …

[HTML][HTML] Targeting autophagy and beyond: deconvoluting the complexity of Beclin-1 from biological function to cancer therapy

J Ye, J Zhang, Y Zhu, L Wang, X Jiang, B Liu… - … Pharmaceutica Sinica B, 2023 - Elsevier
Beclin-1 is the firstly-identified mammalian protein of the autophagy machinery, which
functions as a molecular scaffold for the assembly of PI3KC3 (class III phosphatidylinositol 3 …

Unravelling the complexity of lncRNAs in autophagy to improve potential cancer therapy

Y Wang, Y Fu, Y Lu, S Chen, J Zhang, B Liu… - Biochimica et Biophysica …, 2023 - Elsevier
Autophagy is well-known as an internal catabolic process that is evolutionarily conserved
and performs the key biological function in maintaining cellular homeostasis. It is tightly …

Lnclocator-imb: An Imbalance-tolerant Ensemble Deep Learning Framework for Predicting Long Non-coding RNA Subcellular Localization

H Liu, D Li, H Wu - IEEE Journal of Biomedical and Health …, 2023 - ieeexplore.ieee.org
Recent studies have highlighted the critical roles of long non-coding RNAs (lncRNAs) in
various biological processes, including but not limited to dosage compensation, epigenetic …

Long non‐coding RNA HOXC‐AS1 exerts its oncogenic effects in esophageal squamous cell carcinoma by interaction with IGF2BP2 to stabilize SIRT1 expression

Z Yang, J Wan, L Ma, Z Li, R Yang… - Journal of Clinical …, 2023 - Wiley Online Library
Background Long non‐coding RNA HOXC cluster antisense RNA 1 (HOXC‐AS1) is a novel
lncRNA whose cancer‐promoting effect in gastric cancer and nasopharyngeal carcinoma …

PTBP1 as a potential regulator of disease

Q Yu, T Wu, W Xu, J Wei, A Zhao, M Wang, M Li… - Molecular and Cellular …, 2023 - Springer
Polypyrimidine tract-binding protein 1 (PTBP1) is a member of the heterogeneous nuclear
ribonucleoprotein (hnRNP) family, which plays a key role in alternative splicing of precursor …

LncRNA FIRRE regulated endometrial cancer radiotherapy sensitivity via the miR-199b-5p/SIRT1/BECN1 axis-mediated autophagy

J Cai, R Wang, Y Chen, C Zhang, L Fu, C Fan - Genomics, 2024 - Elsevier
Background Endometrial cancer (EC) poses a serious threat to women's health.
Radiotherapy has been widely used for EC treatment. However, the mechanism of FIRRE in …