Frugivory evolved multiple times in mammals, including bats. However, the cellular and
molecular components driving it remain largely unknown. Here, we used integrative single …

Polycystic kidney disease (PKD) is an important cause of end stage renal disease, but
treatment options are limited. While later stages of the disease have been extensively …

Despite recent advances made in short-term outcomes; minimal improvements have been
observed in long-term kidney transplantation outcomes. Due to an imbalance between …

Hypertension is common in the general population. Management of hypertensive patients at
risk of hyperkalemia is challenging due to potential life-threatening complications such as …

Flow‐induced shear stress affects renal epithelial cells in the nephron tubule with potential
implications for differential functionalities of the individual segments. Disruptions of cellular …

Since the publication of the first edition of this book in 2010, an explosion of spectacular
discoveries in the field of regeneration has compelled the current revisit of the field of …

Recent advances in the molecular interrogation of the genome, transcriptome, proteome,
and metabolome now position nephrology at the cusp of innovation, especially to address …

Loss of a kidney results in compensatory growth of the remaining kidney, a phenomenon of
considerable clinical importance. However, the mechanisms involved are largely unknown …

Backgrounds: The clinical features of autosomal dominant polycystic kidney disease
(ADPKD) differ among patients even if they have the same gene mutation in PKD1 or PKD2 …

The fluid in the 14 distinct segments of the renal tubule undergoes sequential transport
processes that gradually convert the glomerular filtrate into the final urine. The solute carrier …