The role of interleukin-8 in lung inflammation and injury: implications for the management of COVID-19 and hyperinflammatory acute respiratory distress syndrome

MC Cesta, M Zippoli, C Marsiglia, EM Gavioli… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus—2 (SARS CoV-2) has resulted in the
global spread of Coronavirus Disease 2019 (COVID-19) and an increase in complications …

[HTML][HTML] The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions

V Carlini, DM Noonan, E Abdalalem, D Goletti… - Frontiers in …, 2023 - frontiersin.org
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis

MC Cesta, M Zippoli, C Marsiglia… - European Journal of …, 2023 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is an acute inflammatory condition with a
dramatic increase in incidence since the beginning of the coronavirus disease 19 (COVID …

Association between inflammatory cytokines and anti-SARS-CoV-2 antibodies in hospitalized patients with COVID-19

X Jing, M Xu, D Song, T Yue, Y Wang, P Zhang… - Immunity & …, 2022 - Springer
Background COVID-19 patients may experience “cytokine storm” when human immune
system produces excessive cytokines/chemokines. However, it remains unclear whether …

[PDF][PDF] Integrated miRNA/cytokine/chemokine profiling reveals severity-associated step changes and principal correlates of fatality in COVID-19

JC Wilson, D Kealy, SR James, T Plowman, K Newling… - IScience, 2022 - cell.com
Inflammatory cytokines and chemokines (CC) drive COVID-19 pathology. Yet, patients with
similar circulating CC levels present with different disease severity. Here, we determined …

[HTML][HTML] Profile of circulatory cytokines and chemokines in human coronaviruses: a systematic review and meta-analysis

A Zawawi, AY Naser, H Alwafi, F Minshawi - Frontiers in Immunology, 2021 - frontiersin.org
Background SARS, MERS, and COVID-19 share similar characteristics. For instance, the
genetic homology of SARS-CoV-2 compared to SARS-CoV and MERS-CoV is 80% and …

Microfluidic magnetic analyte delivery technique for separation, enrichment, and fluorescence detection of ultratrace biomarkers

J Yang, X Xiao, L Xia, G Li, L Shui - Analytical Chemistry, 2021 - ACS Publications
A microfluidic magnetic analyte delivery (μMAD) technique was developed to realize sample
preparation and ultrasensitive biomarker detection. A simply designed microfluidic device …

Preliminary evidence for IL-10-Induced ACE2 mRNA expression in lung-derived and endothelial cells: implications for SARS-Cov-2 ARDS pathogenesis

A Albini, L Calabrone, V Carlini, N Benedetto… - Frontiers in …, 2021 - frontiersin.org
Angiotensin-converting enzyme 2 (ACE2) is a receptor for the spike protein of SARS-COV-2
that allows viral binding and entry and is expressed on the surface of several pulmonary and …

Potential immune indicators for predicting the prognosis of COVID-19 and trauma: similarities and disparities

H Fouladseresht, A Ghamar Talepoor… - Frontiers in …, 2022 - frontiersin.org
Although cellular and molecular mediators of the immune system have the potential to be
prognostic indicators of disease outcomes, temporal interference between diseases might …

Does SARS-CoV-2 induce IgG4 synthesis to evade the immune system?

A Rubio-Casillas, EM Redwan, VN Uversky - Biomolecules, 2023 - mdpi.com
SARS-CoV-2, the virus that causes the COVID-19 disease, has been shown to cause
immune suppression in certain individuals. This can manifest as a reduced ability of the …