Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

[HTML][HTML] Long COVID: pathophysiological factors and abnormalities of coagulation

S Turner, MA Khan, D Putrino, A Woodcock… - Trends in Endocrinology …, 2023 - cell.com
Acute COVID-19 infection is followed by prolonged symptoms in approximately one in ten
cases: known as Long COVID. The disease affects~ 65 million individuals worldwide. Many …

2022 ACC expert consensus decision pathway on cardiovascular sequelae of COVID-19 in adults: myocarditis and other myocardial involvement, post-acute …

Writing Committee, TJ Gluckman, NM Bhave… - Journal of the American …, 2022 - jacc.org
The American College of Cardiology (ACC) has a long history of developing documents (eg,
decision pathways, health policy statements, appropriate use criteria) to provide members …

Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)

M Haffke, H Freitag, G Rudolf, M Seifert… - Journal of Translational …, 2022 - Springer
Background Fatigue, exertion intolerance and post-exertional malaise are among the most
frequent symptoms of Post-COVID Syndrome (PCS), with a subset of patients fulfilling …

[HTML][HTML] Muscle abnormalities worsen after post-exertional malaise in long COVID

B Appelman, BT Charlton, RP Goulding… - Nature …, 2024 - nature.com
A subgroup of patients infected with SARS-CoV-2 remain symptomatic over three months
after infection. A distinctive symptom of patients with long COVID is post-exertional malaise …

[HTML][HTML] Long COVID: the nature of thrombotic sequelae determines the necessity of early anticoagulation

C Wang, C Yu, H Jing, X Wu, VA Novakovic… - Frontiers in Cellular …, 2022 - frontiersin.org
Many discharged COVID-19 patients affected by sequelae experience reduced quality of life
leading to an increased burden on the healthcare system, their families and society at large …

Long COVID and the cardiovascular system—elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint …

M Gyöngyösi, P Alcaide, FW Asselbergs… - Cardiovascular …, 2023 - academic.oup.com
Long COVID has become a world-wide, non-communicable epidemic, caused by long-
lasting multiorgan symptoms that endure for weeks or months after SARS-CoV-2 infection …

[HTML][HTML] Post-COVID syndrome

M Hallek, K Adorjan, U Behrends, G Ertl… - Deutsches Ärzteblatt …, 2023 - ncbi.nlm.nih.gov
Background As defined by the WHO, the term post-COVID syndrome (PCS) embraces a
group of symptoms that can occur following the acute phase of a SARS-CoV-2 infection and …

Long COVID: major findings, mechanisms and recommendations

HE Davis, L McCorkell, JM Vogel… - Nature Reviews …, 2023 - nature.com
Long COVID is an often debilitating illness that occurs in at least 10% of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. More than 200 symptoms …

Post-acute sequelae of COVID-19 is characterized by diminished peripheral CD8+β7 integrin+ T cells and anti-SARS-CoV-2 IgA response

A Santa Cruz, A Mendes-Frias… - Nature …, 2023 - nature.com
Several millions of individuals are estimated to develop post-acute sequelae SARS-CoV-2
condition (PASC) that persists for months after infection. Here we evaluate the immune …