Background/Aim. Toll‐like receptors (TLRs) are pivotal biomolecules in the immune system. Today, we are all aware of the importance of TLRs in bridging innate and adaptive immune …
Parasites and infectious diseases are everywhere and represent some of the most potent forces shaping the natural world. They affect almost every aspect imaginable in the life of …
Macrophages derived from monocyte precursors undergo specific polarization processes which are influenced by the local tissue environment: classically activated (M1) …
Metabolic processes play a critical role in immune regulation. Metabolomics is the systematic analysis of small molecules (metabolites) in organisms or biological samples …
Radiotherapy is a primary therapeutic modality widely utilized with curative intent. Traditionally tumor response was hypothesized to be due to high levels of cell death …
R Eftimie, A Mavrodin, SPA Bordas - Advances in Applied Mechanics, 2023 - Elsevier
The last few decades have been dominated by the need for digital control of various processes in biology and medicine. Advances in artificial intelligence (AI) over the last few …
SM Ciupe, JM Heffernan - Infectious Disease Modelling, 2017 - Elsevier
Understanding the mechanisms governing host-pathogen kinetics is important and can guide human interventions. In-host mathematical models, together with biological data, have …
In this work, we develop mathematical models of the immune response to respiratory viral infection, taking into account some particular properties of the SARS-CoV infections …
Antibody–drug conjugate (ADC) development has evolved greatly over the last 3 decades, including the Food and Drug Administration (FDA) approval of several new drugs. However …