Social physics

M Jusup, P Holme, K Kanazawa, M Takayasu, I Romić… - Physics Reports, 2022 - Elsevier
Recent decades have seen a rise in the use of physics methods to study different societal
phenomena. This development has been due to physicists venturing outside of their …

Toll‐like receptors: general molecular and structural biology

P Behzadi, HA García-Perdomo… - Journal of Immunology …, 2021 - Wiley Online Library
Background/Aim. Toll‐like receptors (TLRs) are pivotal biomolecules in the immune system.
Today, we are all aware of the importance of TLRs in bridging innate and adaptive immune …

[图书][B] Evolutionary parasitology: the integrated study of infections, immunology, ecology, and genetics

P Schmid-Hempel - 2021 - books.google.com
Parasites and infectious diseases are everywhere and represent some of the most potent
forces shaping the natural world. They affect almost every aspect imaginable in the life of …

Gene regulatory network modeling of macrophage differentiation corroborates the continuum hypothesis of polarization states

A Palma, AS Jarrah, P Tieri, G Cesareni… - Frontiers in …, 2018 - frontiersin.org
Macrophages derived from monocyte precursors undergo specific polarization processes
which are influenced by the local tissue environment: classically activated (M1) …

Metabolomics meets systems immunology

J Fu, F Zhu, CJ Xu, Y Li - EMBO reports, 2023 - embopress.org
Metabolic processes play a critical role in immune regulation. Metabolomics is the
systematic analysis of small molecules (metabolites) in organisms or biological samples …

[HTML][HTML] Mathematical modeling of radiotherapy and its impact on tumor interactions with the immune system

RA Bekker, S Kim, S Pilon-Thomas, H Enderling - Neoplasia, 2022 - Elsevier
Radiotherapy is a primary therapeutic modality widely utilized with curative intent.
Traditionally tumor response was hypothesized to be due to high levels of cell death …

From digital control to digital twins in medicine: A brief review and future perspectives

R Eftimie, A Mavrodin, SPA Bordas - Advances in Applied Mechanics, 2023 - Elsevier
The last few decades have been dominated by the need for digital control of various
processes in biology and medicine. Advances in artificial intelligence (AI) over the last few …

[HTML][HTML] In-host modeling

SM Ciupe, JM Heffernan - Infectious Disease Modelling, 2017 - Elsevier
Understanding the mechanisms governing host-pathogen kinetics is important and can
guide human interventions. In-host mathematical models, together with biological data, have …

Modelling of the innate and adaptive immune response to SARS viral infection, cytokine storm and vaccination

C Leon, A Tokarev, A Bouchnita, V Volpert - Vaccines, 2023 - mdpi.com
In this work, we develop mathematical models of the immune response to respiratory viral
infection, taking into account some particular properties of the SARS-CoV infections …

Pharmacokinetic and immunological considerations for expanding the therapeutic window of next-generation antibody–drug conjugates

E Khera, GM Thurber - BioDrugs, 2018 - Springer
Antibody–drug conjugate (ADC) development has evolved greatly over the last 3 decades,
including the Food and Drug Administration (FDA) approval of several new drugs. However …