Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

The inflammaging concept was introduced in 2000 by Prof. Franceschi. This was an
evolutionary or rather a revolutionary conceptualization of the immune changes in response …

The coronavirus disease 2019 (COVID-19) pandemic has elicited a swift response by the
scientific community to elucidate the pathogenesis of severe acute respiratory syndrome …

Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …

Remodelling of the immune system with age—immunosenescence—is a substantial
contributor to poor health in older adults, with increasing risk of infections, cancer and …

Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

Ageing is a global burden. Increasing age is associated with increased incidence of
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …

People worldwide are living longer, and it is estimated that by 2050, the proportion of the
world's population over 60 years of age will nearly double. Natural lung aging is associated …

Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …