Targeting ferroptosis as a promising therapeutic strategy for ischemia-reperfusion injury

Y Pan, X Wang, X Liu, L Shen, Q Chen, Q Shu - Antioxidants, 2022 - mdpi.com
Ischemia-reperfusion (I/R) injury is a major challenge in perioperative medicine that
contributes to pathological damage in various conditions, including ischemic stroke …

The ACSL4 network regulates cell death and autophagy in diseases

F Chen, R Kang, J Liu, D Tang - Biology, 2023 - mdpi.com
Simple Summary ACSL4 is an enzyme involved in the intracellular conversion of long-chain
fatty acids and coenzyme A into fatty-acid coenzymes. It plays a vital role in various …

Advances in the study of B cells in renal ischemia-reperfusion injury

H Fan, J Liu, J Sun, G Feng, J Li - Frontiers in Immunology, 2023 - frontiersin.org
Renal ischemia-reperfusion injury (IRI) is a non-negligible clinical challenge for clinicians in
surgeries such as renal transplantation. Functional loss of renal tubular epithelial cell (TEC) …

Necrostatin-1 alleviates lung ischemia-reperfusion injury via inhibiting necroptosis and apoptosis of lung epithelial cells

L Dong, F Liang, Z Lou, Y Li, J Li, Y Chen, J Ding… - Cells, 2022 - mdpi.com
Lung ischemia-reperfusion injury (LIRI) is associated with many diseases, including primary
graft dysfunction after lung transplantation, and has no specific and effective therapies …

Pathophysiology and targeted treatment of cholesterol crystal embolism and the related thrombotic angiopathy

C Shi, E Mammadova‐Bach, C Li… - The FASEB …, 2023 - epub.ub.uni-muenchen.de
Cholesterol crystal (CC) embolism is a complication of advanced atherosclerotic plaques
located in the major arteries. This pathological condition is primarily induced by …

Nanomedicine in kidney disease

B Bishop, S Sharma, EA Scott - Current opinion in nephrology and …, 2023 - journals.lww.com
Nanomedicine in kidney disease : Current Opinion in Nephrology and Hypertension
Nanomedicine in kidney disease : Current Opinion in Nephrology and Hypertension Log in or …

Ferroptosis in organ ischemia–reperfusion injuries: recent advancements and strategies

X Luan, P Chen, L Miao, X Yuan, C Yu, G Di - Molecular and Cellular …, 2024 - Springer
Ferroptosis is a newly discovered type of regulated cell death participated in multiple
diseases. Different from other classical cell death programs such as necrosis and apoptosis …

A Proteomic Study of the Bioactivity of Annona muricata Leaf Extracts in HT-1080 Fibrosarcoma Cells

AD Marrero, AR Quesada, B Martínez-Poveda… - International Journal of …, 2023 - mdpi.com
Graviola (Annona muricata) is a tropical plant with many traditional ethnobotanic uses and
pharmacologic applications. A metabolomic study of both aqueous and DMSO extracts from …

Dysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death

GE Lee, G Bang, J Byun, CJ Lee, W Chen… - … & Molecular Medicine, 2024 - nature.com
Cancer cells often exhibit resistance to apoptotic cell death, but they may be vulnerable to
other types of cell death. Elucidating additional mechanisms that govern cancer cell death is …

Neuroprotective and antioxidant properties of CholesteroNitrone ChN2 and QuinolylNitrone QN23 in an experimental model of cerebral ischemia: involvement of …

B Chamorro, S Izquierdo-Bermejo… - Antioxidants, 2023 - mdpi.com
Ischemic stroke is the leading cause of disability and the second leading cause of death
worldwide. However, current therapeutic strategies are scarce and of limited efficacy. The …