[HTML][HTML] Epigallocatechin-3-gallate confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis, apoptosis, and autophagy via …

T Hu, FJ Hu, H Huang, ZY Zhang, YM Qiao… - Biomedicine & …, 2024 - Elsevier
Previous studies have demonstrated that the underlying mechanisms of myocardial
ischemia/reperfusion injury (MIRI) are complex and involve multiple types of regulatory cell …

ROS-responsive MSC-derived Exosome Mimetics Carrying MHY1485 Alleviate Renal Ischemia Reperfusion Injury through Multiple Mechanisms

Z Qian, X Zhang, J Huang, X Niu, C Zhu, Z Tai… - ACS …, 2024 - ACS Publications
Renal ischemia reperfusion (IR) injury is a prevalent inflammatory nephropathy in surgeries
such as renal transplantation or partial nephrectomy, damaging renal function through …

The advancement of polysaccharides in disease modulation: Multifaceted regulation of programmed cell death

L Luo, F Feng, A Zhong, N Guo, J He, C Li - International Journal of …, 2024 - Elsevier
Programmed cell death (PCD), also known as regulatory cell death (RCD), is a process that
occurs in all organisms and is closely linked to both normal physiological processes and …

Neuregulin-1, a member of the epidermal growth factor family, mitigates STING-mediated pyroptosis and necroptosis in ischaemic flaps

X Zhu, G Yu, Y Lv, N Yang, Y Zhao, F Li, J Zhao… - Burns & …, 2024 - academic.oup.com
Background Ensuring the survival of the distal end of a random flap during hypoperfusion
(ischaemia) is difficult in clinical practice. Effective prevention of programmed cell death is a …

New insights into renal fibrosis and therapeutic effects of natural products volume II

DQ Chen, Y Guo, ZY Guo, YP Tang - Frontiers in Pharmacology, 2022 - frontiersin.org
Renal fibrosis which begins as an abnormal tissue regeneration process is the final and
common outcome of various chronic kidney diseases (CKD)(Li et al., 2022). Sustained …

Ruthenium red alleviates post-resuscitation myocardial dysfunction by upregulating mitophagy through inhibition of USP33 in a cardiac arrest rat model

F Zhang, Z Ye, Y Ran, C Liu, M Zhang, X Xu… - European Journal of …, 2024 - Elsevier
Cardiac arrest (CA) remains a leading cause of death, with suboptimal survival rates despite
efforts involving cardiopulmonary resuscitation and advanced life-support technology. Post …

Remimazolam Improves the Markers of Post-Resuscitation Cerebral Injury in a Swine Model of Cardiac Arrest

R Shen, Z Liu, L Fei, Y Zhang, L Xu, C Xuan - Shock, 2023 - journals.lww.com
Methods A total of 24 swine were utilized in this study, in which the animals were randomly
divided into the following three groups: Sham group (n= 6), CPR group (n= 9), and CPR+ RP …

Disulfiram downregulates ferredoxin 1 to maintain copper homeostasis and inhibit inflammation in cerebral ischemia/reperfusion injury.

S Yang, X Li, J Yan, F Jiang, X Fan, J Jin, W Zhang… - 2024 - researchsquare.com
In the current study, we aimed to investigate whether disulfiram (DSF) plays a
neuroprotective role in cerebral ischemia-reperfusion (CI-RI) injury by regulating ferredoxin …

Mechanism of berberine regulating ox-LDL induced endothelial pyroptosis based on TXNIP/NLRP3/GSDMD pathway

莉莉于 - 2023 - researchsquare.com
This study aimed to explore the regulatory effect of berberine on ox LDL induced HUVECs
pyroptosis, and reveal the possible molecular mechanism and target of berberine in …