[PDF][PDF] Main Manuscript for Structural basis for p53 binding to its nucleosomal target DNA sequence

M Nishimura, Y Takizawa, K Nozawa, H Kurumizaka… - 2022 - scholar.archive.org
The tumor suppressor p53 functions as a pioneer transcription factor that binds a
nucleosomal target DNA sequence. However, the mechanism by which p53 binds to its …

Genomregulation durch Tumorsuppressoren und Onkoproteine

M Fischer - BIOspektrum, 2024 - Springer
Genomregulation durch Tumorsuppressoren und Onkoproteine Page 1 BIOspektrum | 01.24 |
30. Jahrgang 123 KARRIERE, KÖPFE & KONZEPTE Martin Fischer 2006–2011 B. Sc. und M …

Overcoming drug resistance: targeting the BCL-2 family and the long non-coding RNA HCP5 in medulloblastoma and colorectal cancer

A Iseghohimen - 2023 - salford-repository.worktribe.com
Colorectal cancer (CRC) is one of the most common cancers in the UK and
medulloblastoma is a common cancer found in children. While there has been a progressive …

Tumour evolution in a single patient

TJ Robb - 2021 - researchspace.auckland.ac.nz
Tumour evolution underlies many of the most pressing challenges facing precision oncology
today, indicating that a better understanding of tumour evolution has the potential to improve …

Nonilfenolün malignant melanoma hücresi g-361 üzerine etkisi

E Bilici - 2022 - acikerisim.aku.edu.tr
Nonilfenol en çok kullanılan ve maruz kaldığımız endokrin bozucular arasında yer alır.
Endokrin bozucuların kanserojen etkileri ile ilgili çok sayıda çalışma olmasına rağmen …

The WRAP53α gene undergoes p53 tumor suppressor-dependent transcriptional regulation in response to DNA damage

AH Moxley, D Reisman - Gene Reports, 2022 - Elsevier
The Wrap53α mRNA transcript regulates expression of the p53 tumor suppressor gene by
interacting with the 5-untranslated region of the p53 mRNA transcript. The interaction of p53 …

[PDF][PDF] BBA-Reviews on Cancer

M Fischer - researchgate.net
The transcription factor p53 is activated in response to a variety of cellular stresses and
serves as a prominent and potent tumor suppressor. Since its discovery, we have sought to …

Enhanced Efficacy of Aurora Kinase Inhibitors in G2/M Checkpoint Deficient TP53 Mutant Uterine Carcinomas Is Linked to the Summation of LKB1–AKT–p53 …

KN Lynch, JF Liu, N Kesten, KH Chow, A Shetty, R He… - Cancers, 2021 - mdpi.com
Simple Summary Cancers arising from the lining of the uterus, endometrial cancers, are the
most common gynecologic malignancy in the United States. Once endometrial cancer …

[PDF][PDF] Journal of Cancer Science Research & Therapy

AH Moxley, D Reisman - 2022 - manuscriptscientific.com
The Wrap53 mRNA transcript regulates expression of the p53 tumor suppressor gene by
interacting with the 5'-untranslated region of the p53 mRNA transcript. The interaction of p53 …

Activating STING-Dependent Immune Signaling in AML

AA Kogan - 2021 - search.proquest.com
DNA methyltransferase inhibitors (DNMTis) are an epigenetic therapy for acute myeloid
leukemia (AML) patients unfit for or unlikely to respond to intensive chemotherapy. DNMTis …