State-of-the-art-review Mechanisms of action of SGLT2 inhibitors and clinical implications
V Vallon - American Journal of Hypertension, 2024 - academic.oup.com
Inhibitors of the Na+-coupled glucose transporter SGLT2 (SGLT2i) primarily shift the
reabsorption of large amounts of glucose from the kidney's early proximal tubule to …
reabsorption of large amounts of glucose from the kidney's early proximal tubule to …
Biology of the proximal tubule in body homeostasis and kidney disease
The proximal tubule (PT) is known as the workhorse of the kidney, both for the range and
magnitude of the functions that it performs. It is not only responsible for reabsorbing most …
magnitude of the functions that it performs. It is not only responsible for reabsorbing most …
From the Beginning to the End: Effects of Proteinuria along the Renal Tubule
LMS Gerhardt - Journal of the American Society of Nephrology, 2024 - journals.lww.com
Kidneys are essential regulators of fluid and electrolyte homeostasis and clear the body of
waste products by processing about 900 L of blood plasma every day to produce 180 L of …
waste products by processing about 900 L of blood plasma every day to produce 180 L of …