Infectious keratitis

PA Thomas, P Geraldine - Current opinion in infectious diseases, 2007 - journals.lww.com
Improved modalities of diagnosis and treatment have improved the outcome of infectious
keratitis, but therapy of acanthamoebal, fungal and P. aeruginosa keratitis is still a …

Corneal infection models: tools to investigate the role of biofilms in bacterial keratitis

L Urwin, K Okurowska, G Crowther, S Roy, P Garg… - Cells, 2020 - mdpi.com
Bacterial keratitis is a corneal infection which may cause visual impairment or even loss of
the infected eye. It remains a major cause of blindness in the developing world …

Cytokeratins mediate epithelial innate defense through their antimicrobial properties

C Tam, JJ Mun, DJ Evans… - The Journal of clinical …, 2012 - Am Soc Clin Investig
Epithelial cells express antimicrobial proteins in response to invading pathogens, although
little is known regarding epithelial defense mechanisms during healthy conditions. Here we …

Antimicrobial resistance trends in bacterial keratitis over 5 years in Sydney, Australia

M Cabrera‐Aguas, P Khoo… - Clinical & …, 2020 - Wiley Online Library
Importance Antimicrobial resistance (AMR) patterns in bacterial keratitis may fluctuate in a
geographic location over time. Background To investigate any change in AMR patterns in …

[HTML][HTML] All-small-molecule supramolecular hydrogels assembled from guanosine 5′-monophosphate disodium salt and tobramycin for the treatment of bacterial …

X Cheng, H Chen, F Yang, J Hong, Y Cheng, J Hu - Bioactive Materials, 2022 - Elsevier
Bacterial keratitis is the most common corneal infection which may lead to blindness, and
seriously threatened the human visual health worldwide. Clinical treatment with antibiotic …

Evolving risk factors and antibiotic sensitivity patterns for microbial keratitis at a large county hospital

H Jin, WT Parker, NW Law, CL Clarke… - British Journal of …, 2017 - bjo.bmj.com
Purpose: To identify the risk factors, causative organisms, antimicrobial susceptibility and
outcomes of microbial keratitis in a large county hospital in Houston, Texas. Design: Case …

Antibiotics-free nanomaterials against bacterial keratitis: Eliminating infections with reactive oxygen species (ROS)

L Zhou, Y Deng, Y Ren, HL Poon, WY Chu… - Chemical Engineering …, 2024 - Elsevier
Bacterial keratitis (BK), which accounts for over 50% of the reported cases of microbial
keratitis, is a condition that can result in vision loss and blindness if left untreated. Antibiotics …

Current concepts on Pseudomonas aeruginosa interaction with human airway epithelium

A Muggeo, C Coraux, T Guillard - PLoS pathogens, 2023 - journals.plos.org
Pseudomonas aeruginosa is a major, but opportunistic, respiratory pathogen, which rarely
infects healthy individuals, mainly due to the barrier effect of the human airway epithelium …

Queensland microbial keratitis database: 2005–2015

M Green, N Carnt, A Apel, F Stapleton - British Journal of …, 2019 - bjo.bmj.com
Aims To estimate the incidence of culture-positive microbial keratitis in Queensland and
analyse trends in the organisms and their sensitivities cultured from corneal scrapes …

Carboxylated nanofibrillated cellulose empowers moxifloxacin to overcome Staphylococcus aureus biofilm in bacterial keratitis

M Malani, AT Thodikayil, S Saha, J Nirmal - Carbohydrate Polymers, 2024 - Elsevier
Bacterial keratitis is one of the vision-threatening ocular diseases that is increasing at an
alarming rate due to antimicrobial resistance. One of the primary causes of antimicrobial …