Idiopathic pulmonary fibrosis (IPF) is the representative phenotype of interstitial lung disease
where severe scarring develops in the lung interstitium. Although antifibrotic treatments are …

Idiopathic pulmonary fibrosis (IPF) is the most common fibrotic form of idiopathic diffuse lung
disease. Due to limited treatment options, IPF patients suffer from poor survival. About ten …

Fibrosis can occur in all major organs with relentless progress, ultimately leading to organ
failure and potentially death. Unfortunately, current clinical treatments cannot prevent or …

Background PM2. 5 exposure increases asthma exacerbation risk and worsens airway
inflammation and mucus secretion, but the underlying mechanisms, especially the …

The pathogenesis of pulmonary fibrosis, including idiopathic pulmonary fibrosis (IPF) and
other forms of interstitial lung disease, involves a complex interplay of various factors …

As a fatal occupational disease with limited therapeutic options, molecular mechanisms
underpinning silicosis are still undefined. Herein, single-cell RNA sequencing of the lung …

Fibrotic hypersensitivity pneumonitis (FHP) is a fatal interstitial pulmonary disease with
limited treatment options. Lung macrophages are a heterogeneous cell population that …

Neuronal death is one of the key pathologies in Alzheimer's disease (AD). How neuronal
death begins in AD is far from clear, so clarifying this process may help develop effective …

Metal regulatory transcription factor 1 (MTF1) has been reported to be correlated with
several human diseases, especially like cancers. Exploring the underlying mechanisms and …

Hypersensitivity pneumonitis (HP), an immune-mediated subtype of interstitial lung diseases
(ILDs), is mediated by repetitive inhalation of certain antigens. Transcriptomic signatures …