The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

[HTML][HTML] Candida sp. Infections in Patients with Diabetes Mellitus

CF Rodrigues, ME Rodrigues, M Henriques - Journal of clinical medicine, 2019 - mdpi.com
Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

[HTML][HTML] Candida and Candidiasis—Opportunism Versus Pathogenicity: A Review of the Virulence Traits

CN Ciurea, IB Kosovski, AD Mare, F Toma… - Microorganisms, 2020 - mdpi.com
One of the most important questions in microbiology nowadays, is how apparently harmless,
commensal yeasts like Candida spp. can cause a rising number of infections. The …

[HTML][HTML] Metabolism impacts upon Candida immunogenicity and pathogenicity at multiple levels

AJP Brown, GD Brown, MG Netea, NAR Gow - Trends in microbiology, 2014 - cell.com
Metabolism is integral to the pathogenicity of Candida albicans, a major fungal pathogen of
humans. As well as providing the platform for nutrient assimilation and growth in diverse …

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen

IV Ene, AK Adya, S Wehmeier, AC Brand… - Cellular …, 2012 - Wiley Online Library
The survival of all microbes depends upon their ability to respond to environmental
challenges. To establish infection, pathogens such as C andida albicans must mount …

Candida survival strategies

M Polke, B Hube, ID Jacobsen - Advances in Applied Microbiology, 2015 - Elsevier
Only few Candida species, eg, Candida albicans, Candida glabrata, Candida dubliniensis,
and Candida parapsilosis, are successful colonizers of a human host. Under certain …

Stress adaptation in a pathogenic fungus

AJP Brown, S Budge, D Kaloriti… - Journal of …, 2014 - journals.biologists.com
Candida albicans is a major fungal pathogen of humans. This yeast is carried by many
individuals as a harmless commensal, but when immune defences are perturbed it causes …

[HTML][HTML] Host Cell Invasion and Virulence Mediated by Candida albicans Ssa1

JN Sun, NV Solis, QT Phan, JS Bajwa… - PLoS …, 2010 - journals.plos.org
Candida albicans Ssa1 and Ssa2 are members of the HSP70 family of heat shock proteins
that are expressed on the cell surface and function as receptors for antimicrobial peptides …

[HTML][HTML] Sugar Sensing and Signaling in Candida albicans and Candida glabrata

M Van Ende, S Wijnants, P Van Dijck - Frontiers in microbiology, 2019 - frontiersin.org
Candida species, such as Candida albicans and Candida glabrata, cause infections at
different host sites because they adapt their metabolism depending on the available …

[HTML][HTML] Adapting to survive: How Candida overcomes host-imposed constraints during human colonization

R Alves, C Barata-Antunes, M Casal, AJP Brown… - PLoS …, 2020 - journals.plos.org
Successful human colonizers such as Candida pathogens have evolved distinct strategies
to survive and proliferate within the human host. These include sophisticated mechanisms to …