Context: For health care planning and allocation of resources, realistic estimation of the
prevalence of primary aldosteronism is necessary. Reported prevalences of primary …

In the 60 years that have passed since the discovery of the mineralocorticoid hormone
aldosterone, much has been learned about its synthesis (both adrenal and extra-adrenal) …

Autonomous aldosterone overproduction represents the underlying condition of 5–10% of
patients with arterial hypertension and carries a significant burden of mortality and morbidity …

Background Experimental and human studies demonstrate that long-term exposure to
elevated aldosterone levels results in cardiac and vascular damage. Methods We …

ContextExperimental animal studies indicate that exposure to increased aldosterone levels
might result in renal damage, but the clinical evidence supporting this role of aldosterone is …

Adrenal vein sampling has a reputation as a difficult procedure. However, it is being
performed more frequently at some institutions due to the realization that primary …

Although the aldosterone/renin ratio (ARR) is the most reliable screening test for primary
aldosteronism, false positives and negatives occur. Dietary salt restriction, concomitant …

Context: The relationship between aldosterone and glucose metabolism is poorly
understood, and there is substantial disparity among findings of studies that have examined …

Background: The ratio of plasma aldosterone concentration to plasma renin activity (PRA) is
considered the screening test of choice for primary aldosteronism. Uncertainty exists …

Background: Measurement of plasma renin is important for the clinical assessment of
hypertensive patients. The most common methods for measuring plasma renin are the …