[HTML][HTML] Attenuated initial serum ferritin concentration in critically ill coronavirus disease 2019 geriatric patients with comorbid psychiatric conditions

OA Abulseoud, A Yehia, CJ Egol, VN Nettey… - Frontiers in …, 2022 - frontiersin.org
We examined the effects of psychiatric comorbidity, sex, and ICU admission on serum ferritin
concentration in 628 elderly patients (79.7±8.5 years) with positive SARS-CoV-2 PCR test …

Microfluidic Immunoarray for Point-of-Care Detection of Cytokines in COVID-19 Patients

KS Bhalerao, PIT De Silva, K Hiniduma… - ACS …, 2024 - ACS Publications
The “cytokine storm” often induced in COVID-19 patients contributes to the onset of “acute
respiratory distress syndrome”(ARDS) accompanied by lung infection and damage …

[HTML][HTML] Application of Machine Learning in Hospitalized Patients with Severe COVID-19 Treated with Tocilizumab

A Ramón, M Zaragozá, AM Torres, J Cascón… - Journal of Clinical …, 2022 - mdpi.com
Among the IL-6 inhibitors, tocilizumab is the most widely used therapeutic option in patients
with SARS-CoV-2-associated severe respiratory failure (SRF). The aim of our study was to …

[HTML][HTML] A randomised, double-blind, placebo-controlled, multicentre clinical trial of AZD1656 in diabetic patients hospitalised with COVID-19: The ARCADIA Trial …

J Chorlton, Z Hollowood, C Dyer, D Lockhart… - …, 2022 - thelancet.com
Background A potential immunotherapeutic role for AZD1656 (a glucokinase activator) in the
treatment of COVID-19 was hypothesized. The ARCADIA trial investigated the safety and …

[HTML][HTML] Filariasis research–from basic research to drug development and novel diagnostics, over a decade of research at the Institute for Medical Microbiology …

I Karunakaran, M Ritter, K Pfarr… - Frontiers in tropical …, 2023 - frontiersin.org
Filariae are vector borne parasitic nematodes, endemic in tropical and subtropical regions
causing avoidable infections ranging from asymptomatic to stigmatizing and disfiguring …

Mesenchymal stem cell treatment for hyperactive immune response in patients with COVID-19

R Manoharan, RA Kore, JL Mehta - Immunotherapy, 2022 - Taylor & Francis
The human immune system protects the body against invasive organisms and kicks into a
hyperactive mode in COVID-19 patients, particularly in those who are critically sick …

Simultaneous detection of sepsis host response biomarkers in whole blood using electrochemical biosensor

AS Tanak, A Sardesai, S Muthukumar… - Bioengineering & …, 2022 - Wiley Online Library
Sepsis is a silent killer, caused by a syndromic reaction of the body's immune system to an
infection that is typically the ultimate pathway to mortality due to numerous infectious …

[HTML][HTML] Unbalanced networks and disturbed kinetics of serum soluble mediators associated with distinct disease outcomes in severe COVID-19 patients

GP Jardim-Santos, HL Schulte, PS Kurizky… - Frontiers in …, 2022 - frontiersin.org
The present study applied distinct models of descriptive analysis to explore the integrative
networks and the kinetic timeline of serum soluble mediators to select a set of systemic …

Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators

N Yasmeen, H Selvaraj, SS Lakhawat, M Datta… - Biochemical …, 2023 - Elsevier
Abstract Fatal “cytokine storms (CS)” observed in critically ill COVID-19 patients are
consequences of dysregulated host immune system and over-exuberant inflammatory …

[HTML][HTML] Clinical features of COVID-19 among patients with end-stage renal disease on hemodialysis in the context of high vaccination coverage during the omicron …

NS Beck, S Song, T Park, SH Hong, J Jeong-Eun… - BMC nephrology, 2023 - Springer
Background We determined the clinical presentation and outcomes of the Omicron variant of
severe acute respiratory syndrome coronavirus 2 infection in hemodialysis patients and …